Ten thousand years ago human societies around the globe began to transition from hunting
and gathering to agriculture. By 4000 years ago, ancient peoples had completed the …

Linkage disequilibrium—the nonrandom association of alleles at different loci—is a sensitive
indicator of the population genetic forces that structure a genome. Because of the explosive …

Stochastic simulation is a key tool in population genetics, since the models involved are
often analytically intractable and simulation is usually the only way of obtaining ground-truth …

Understanding the forces that influence natural variation within and among populations has
been a major objective of evolutionary biologists for decades. Motivated by the growth in …

In the past 10years a statistical technique, approximate Bayesian computation (ABC), has
been developed that can be used to infer parameters and choose between models in the …

Recent new methods in Bayesian simulation have provided ways of evaluating posterior
distributions in the presence of analytically or computationally intractable likelihood …

Adaptation from standing genetic variation or recurrent de novo mutation in large
populations should commonly generate soft rather than hard selective sweeps. In contrast to …

A central challenge in evolutionary biology is to identify genes underlying ecologically
important traits and describe the fitness consequences of naturally occurring variation at …

Genome sequence data are now being routinely obtained from many nonmodel organisms.
These data contain a wealth of information about the demographic history of the populations …

Given genomic variation data from multiple individuals, computing the likelihood of complex
population genetic models is often infeasible. To circumvent this problem, we introduce a …