Epistasis and adaptation on fitness landscapes

C Bank - Annual Review of Ecology, Evolution, and Systematics, 2022 - annualreviews.org
Epistasis occurs when the effect of a mutation depends on its carrier's genetic background.
Despite increasing evidence that epistasis for fitness is common, its role during evolution is …

Multivariate selection and the making and breaking of mutational pleiotropy

EI Svensson - Evolutionary Ecology, 2022 - Springer
The role of mutations have been subject to many controversies since the formation of the
Modern Synthesis of evolution in the early 1940ties. Geneticists in the early half of the …

The extinction time under mutational meltdown driven by high mutation rates

L Lansch‐Justen, D Cusseddu… - Ecology and …, 2022 - Wiley Online Library
Mutational meltdown describes an eco‐evolutionary process in which the accumulation of
deleterious mutations causes a fitness decline that eventually leads to the extinction of a …

Population bottleneck has only marginal effect on fitness evolution and its repeatability in dioecious Caenorhabditis elegans

K Bisschop, T Blankers, J Mariën, MT Wortel, M Egas… - …, 2022 - academic.oup.com
The predictability of evolution is expected to depend on the relative contribution of
deterministic and stochastic processes. This ratio is modulated by effective population size …

The extinction time under mutational meltdown

L Lansch-Justen, D Cusseddu, MA Schmitz, C Bank - bioRxiv, 2022 - biorxiv.org
Mutational meltdown describes an eco-evolutionary process in which the accumulation of
deleterious mutations causes a fitness decline that eventually leads to the extinction of a …

Population Genetic Bottleneck has only Marginal Effect on Fitness Evolution and its Repeatability in Dioecious C. Elegans

B Karen, B Thomas, M Janine, WM Tesse, E Martijn… - bioRxiv, 2021 - biorxiv.org
Evolution is a key process by which populations can adapt to novel conditions, but it is not
well understood how predictable this process is. Predictability is expected to depend on the …

Learning from your mistakes: a novel method to predict the response to directional selection

L Milocco - 2021 - ecoevorxiv.org
Predicting how populations respond to selection is a key goal of evolutionary biology. The
field of quantitative genetics provides predictions for the response to directional selection …