Nanoparticles (NPs) have an outstanding position in pharmaceutical, biological, and
medical disciplines. Polymeric NPs based on chitosan (CS) can act as excellent drug …

The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led
to an increasing interest in the development and optimization of drug-delivery systems …

Administration of drugs via the buccal route has attracted much attention in recent years.
However, develo** systems with satisfactory adhesion under wet conditions and …

The popularity of hydrogels as biomaterials lies in their tunable physical properties, ability to
encapsulate small molecules and macromolecular drugs, water holding capacity, flexibility …

The potential of the mucoadhesive film technology is hard to ignore, owing to perceived
superior patient acceptability versus buccal tablets, and significant therapeutic opportunities …

Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Nanoparticles have opened a new perspective for oral drug delivery. However, nanoparticle
transport is strongly hindered by mucus and epithelial barriers before they can enter the …

Buccal drug delivery offers a potential non-invasive means of delivering therapeutics to
patients. Despite the promise, the feasibility of transporting proteins and peptides into …

Oral administration is a widespread and convenient drug delivery approach. However, oral
delivery can be affected by the complex digestive tract environment, including irregular …

Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …