Galangin as an inflammatory response modulator: An updated overview and therapeutic potential

R Thapa, O Afzal, ASA Altamimi, A Goyal… - Chemico-biological …, 2023 - Elsevier
Numerous chronic diseases, such as cancer, diabetes, rheumatoid arthritis, cardiovascular
disease, and gastrointestinal disorders, all have an inflammation-based etiology. In cellular …

Exploring the role of lncrna neat1 knockdown in regulating apoptosis across multiple cancer types: A review

MS Hussain, G Gupta, M Afzal, SM Alqahtani… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators of gene expression,
contributing significantly to a diverse range of cellular processes, including apoptosis. One …

Uncovering the complex role of interferon-gamma in suppressing type 2 immunity to cancer

AA Bhat, A Goyal, R Thapa, I Kazmi, SI Alzarea… - Cytokine, 2023 - Elsevier
Cancer involves cells' abnormal growth and ability to invade or metastasize to different body
parts. Cancerous cells can divide uncontrollably and spread to other areas through the …

A comprehensive review on the emerging role of long non-coding RNAs in the regulation of NF-κB signaling in inflammatory lung diseases

AA Bhat, O Afzal, N Agrawal, R Thapa… - International journal of …, 2023 - Elsevier
Public health globally faces significant risks from conditions like acute respiratory distress
syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and various …

Unlocking the secrets: Volatile Organic Compounds (VOCs) and their devastating effects on lung cancer

MS Hussain, G Gupta, R Mishra, N Patel… - … -Research and Practice, 2024 - Elsevier
Lung cancer (LCs) is still a serious health problem globally, with many incidences attributed
to environmental triggers such as Volatile Organic Compounds (VOCs). VOCs are a broad …

Classic signaling pathways in alveolar injury and repair involved in sepsis‐induced ALI/ARDS: new research progress and prospect

W Li, D Li, Y Chen, H Abudou, H Wang, J Cai… - Disease …, 2022 - Wiley Online Library
Sepsis is a common critical clinical disease with high mortality that can cause approximately
10 million deaths worldwide each year. Acute lung injury (ALI) or acute respiratory distress …

[HTML][HTML] Targeting cancer hallmarks with epigallocatechin gallate (EGCG): mechanistic basis and therapeutic targets

WH Talib, D Awajan, A Alqudah, R Alsawwaf… - Molecules, 2024 - mdpi.com
Epigallocatechin gallate (EGCG) is a catechin, which is a type of flavonoid found in high
concentrations in green tea. EGCG has been studied extensively for its potential health …

DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease

J Chen, T Wang, X Li, L Gao, K Wang… - … and Targeted Therapy, 2024 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterised by persistent airway
inflammation even after cigarette smoking cessation. Neutrophil extracellular traps (NETs) …

Ginsenosides from Panax ginseng as Key Modulators of NF-κB Signaling Are Powerful Anti-Inflammatory and Anticancer Agents

WY Jang, JY Hwang, JY Cho - International Journal of Molecular …, 2023 - mdpi.com
Nuclear factor kappa B (NF-κB) signaling pathways progress inflammation and immune cell
differentiation in the host immune response; however, the uncontrollable stimulation of NF …

Unraveling the impact of miR-21 on apoptosis regulation in glioblastoma

MAJ Shaikh, ASA Altamimi, M Afzal, G Gupta… - … -Research and Practice, 2024 - Elsevier
Glioblastoma is a prevalent form of carcinoma that exhibits a greater incidence rate across
diverse demographics globally. Despite extensive global efforts, GBM continues to be a …