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Staphylococcus aureus host interactions and adaptation
Invasive Staphylococcus aureus infections are common, causing high mortality,
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance
The ecological and evolutionary mechanisms of antimicrobial resistance (AMR) emergence
within patients and how these vary across bacterial infections are poorly understood …
within patients and how these vary across bacterial infections are poorly understood …
PcdA promotes orthogonal division plane selection in Staphylococcus aureus
The bacterial pathogen, Staphylococcus aureus, grows by dividing in two alternating
orthogonal planes. How these cell division planes are positioned correctly is not known …
orthogonal planes. How these cell division planes are positioned correctly is not known …
Within-host evolution of bacterial pathogens in acute and chronic infection
JP Dekker - Annual Review of Pathology: Mechanisms of …, 2024 - annualreviews.org
Bacterial pathogens undergo remarkable adaptive change in response to the selective
forces they encounter during host colonization and infection. Studies performed over the …
forces they encounter during host colonization and infection. Studies performed over the …
Genomic epidemiology of Staphylococcus aureus isolated from bloodstream infections in South America during 2019 supports regional surveillance
S Di Gregorio, J Vielma, MS Haim… - Microbial …, 2023 - microbiologyresearch.org
Staphylococcus aureus remains one of the leading causes of infections worldwide and a
common cause of bacteraemia. However, studies documenting the epidemiology of S …
common cause of bacteraemia. However, studies documenting the epidemiology of S …
Detecting bacterial adaptation within individual microbiomes
TD Lieberman - … Transactions of the Royal Society B, 2022 - royalsocietypublishing.org
The human microbiome harbours a large capacity for within-person adaptive mutations.
Commensal bacterial strains can stably colonize a person for decades, and billions of …
Commensal bacterial strains can stably colonize a person for decades, and billions of …
Antigenic operon fragmentation and diversification mechanism in Bacteroidota impacts gut metagenomics and pathobionts in Crohn's disease microlesions
ABSTRACT Comensal Bacteroidota (Bacteroidota) and Enterobacteriacea are often linked
to gut inflammation. However, the causes for variability of pro-inflammatory surface antigens …
to gut inflammation. However, the causes for variability of pro-inflammatory surface antigens …
The Spx stress regulator confers high-level β-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin-resistant Staphylococcus aureus
TK Nielsen, IB Petersen, L Xu, MD Barbuti… - Antimicrobial Agents …, 2024 - journals.asm.org
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a leading
cause of mortality worldwide. MRSA has acquired resistance to next-generation β-lactam …
cause of mortality worldwide. MRSA has acquired resistance to next-generation β-lactam …
YjbH contributes to Staphylococcus aureus skin pathology and immune response through Agr-mediated α-toxin regulation
AKG McReynolds, EA Pagella, MJ Ridder, O Rippee… - Virulence, 2024 - Taylor & Francis
Staphylococcus aureus is the most common cause of skin and soft tissue infections (SSTIs)
with Methicillin-Resistant S. aureus (MRSA) strains being a major contributor in both …
with Methicillin-Resistant S. aureus (MRSA) strains being a major contributor in both …
[HTML][HTML] Diverse genetic conflicts mediated by molecular mimicry and computational approaches to detect them
In genetic conflicts between intergenomic and selfish elements, driver and killer elements
achieve biased survival, replication, or transmission over sensitive and targeted elements …
achieve biased survival, replication, or transmission over sensitive and targeted elements …