Principles and applications of nucleic acid strand displacement reactions

FC Simmel, B Yurke, HR Singh - Chemical reviews, 2019 - ACS Publications
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

[HTML][HTML] Mastering complexity: towards bottom-up construction of multifunctional eukaryotic synthetic cells

K Göpfrich, I Platzman, JP Spatz - Trends in biotechnology, 2018 - cell.com
With the ultimate aim to construct a living cell, bottom-up synthetic biology strives to
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …

Sculpting and fusing biomimetic vesicle networks using optical tweezers

G Bolognesi, MS Friddin, A Salehi-Reyhani… - Nature …, 2018 - nature.com
Constructing higher-order vesicle assemblies has discipline-spanning potential from
responsive soft-matter materials to artificial cell networks in synthetic biology. This potential …

Functionalization and higher-order organization of liposomes with DNA nanostructures

Z Zhang, Z Feng, X Zhao, D Jean, Z Yu… - Nature …, 2023 - nature.com
Small unilamellar vesicles (SUVs) are indispensable model membranes, organelle mimics,
and drug and vaccine carriers. However, the lack of robust techniques to functionalize or …

Programmed magnetic manipulation of vesicles into spatially coded prototissue architectures arrays

Q Li, S Li, X Zhang, W Xu, X Han - Nature communications, 2020 - nature.com
In nature, cells self-assemble into spatially coded tissular configurations to execute higher-
order biological functions as a collective. This mechanism has stimulated the recent trend in …

Reversible deformation of artificial cell colonies triggered by actin polymerization for muscle behavior mimicry

C Li, X Zhang, B Yang, F Wei, Y Ren, W Mu… - Advanced …, 2022 - Wiley Online Library
The use of artificial cells to mimic living tissues is beneficial for understanding the
mechanism of interaction among cells. Artificial cells hold immense potential in the field of …

Droplet microfluidics for the construction of compartmentalised model membranes

T Trantidou, MS Friddin, A Salehi-Reyhani, O Ces… - Lab on a Chip, 2018 - pubs.rsc.org
The design of membrane-based constructs with multiple compartments is of increasing
importance given their potential applications as microreactors, as artificial cells in synthetic …

Aptamer-functionalized liposomes as a potential treatment for basal cell carcinoma

AN Cadinoiu, DM Rata, LI Atanase, OM Daraba… - Polymers, 2019 - mdpi.com
More than one out of every three new cancers is a skin cancer, and the large majority are
basal cell carcinomas (BCC). Targeted therapy targets the cancer's specific genes, proteins …

Cations regulate membrane attachment and functionality of DNA nanostructures

D Morzy, R Rubio-Sánchez, H Joshi… - Journal of the …, 2021 - ACS Publications
The interplay between nucleic acids and lipids underpins several key processes in
molecular biology, synthetic biotechnology, vaccine technology, and nanomedicine. These …

Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment

M Walczak, RA Brady, L Mancini, C Contini… - Nature …, 2021 - nature.com
Biology has evolved a variety of agents capable of permeabilizing and disrupting lipid
membranes, from amyloid aggregates, to antimicrobial peptides, to venom compounds …