Computational approaches to predict protein–protein interactions in crowded cellular environments

G Grassmann, M Miotto, F Desantis… - Chemical …, 2024 - ACS Publications
Investigating protein–protein interactions is crucial for understanding cellular biological
processes because proteins often function within molecular complexes rather than in …

[HTML][HTML] Alginate-based materials for enzyme encapsulation

Y Weng, G Yang, Y Li, L Xu, X Chen, H Song… - Advances in colloid and …, 2023 - Elsevier
Enzymes are widely used in industry due to their high efficiency and selectivity. However,
their low stability during certain industrial processes can result in a significant loss of …

Exploring the HSA/DNA/lung cancer cells binding behavior of p-Synephrine, a naturally occurring phenyl ethanol amine with anti-adipogenic activity: multi …

R Taheri, N Hamzkanlu, Y Rezvani… - Journal of Molecular …, 2022 - Elsevier
As a phenolic amine, p-Synephrine (SN) is known to exhibit lipolytic properties as well as
enhancing energy expenditure, which can be an excellent alternative to ephedra as a …

New perspective of the ternary complex of nano-curcumin with β-lactoglobulin in the presence of α-lactalbumin: Spectroscopic and molecular dynamic investigations

M Tabasi, P Maghami, Z Amiri-Tehranizadeh… - Journal of Molecular …, 2023 - Elsevier
Understanding the interaction between nano-curcumin (Nano Cur) and proteins is essential
for elucidating the potential therapeutic applications of curcumin in nano formulations. In this …

A guide to studying protein aggregation

JAJ Housmans, G Wu, J Schymkowitz… - The FEBS …, 2023 - Wiley Online Library
Disrupted protein folding or decreased protein stability can lead to the accumulation of
(partially) un‐or misfolded proteins, which ultimately cause the formation of protein …

Thermal stability enhancement: Fundamental concepts of protein engineering strategies to manipulate the flexible structure

M Rahban, S Zolghadri, N Salehi, F Ahmad… - International journal of …, 2022 - Elsevier
Increasing the temperature by just a few degrees may lead to structural perturbation or
unfolding of the protein and consequent loss of function. The concepts of flexibility and …

Structural features, temperature adaptation and industrial applications of microbial lipases from psychrophilic, mesophilic and thermophilic origins

G Rabbani, E Ahmad, A Ahmad, RH Khan - International Journal of …, 2023 - Elsevier
Microbial lipases are very prominent biocatalysts because of their ability to catalyze a wide
variety of reactions in aqueous and non-aqueous media. Here microbial lipases from …

Encoding the atomic structure for machine learning in materials science

S Li, Y Liu, D Chen, Y Jiang, Z Nie… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
In recent years, we have witnessed a widespread application of machine learning
techniques in the field of materials science, owing to the increased availability of research …

Investigation of the interaction behavior between quercetin and pepsin by spectroscopy and MD simulation methods

F Hashemi-Shahraki, B Shareghi… - International Journal of …, 2023 - Elsevier
The ability of a therapeutic compound to bind to proteins is critical for characterizing its
therapeutic impacts. We have selected quercetin (Qu), a most common flavonoid found in …

Protein stability governed by its structural plasticity is inferred by physicochemical factors and salt bridges

AS Panja, S Maiti, B Bandyopadhyay - Scientific reports, 2020 - nature.com
Several organisms, specifically microorganisms survive in a wide range of harsh
environments including extreme temperature, pH, and salt concentration. We analyzed …