Recent advances in contrast-enhanced photoacoustic imaging: overcoming the physical and practical challenges

W Choi, B Park, S Choi, D Oh, J Kim, C Kim - Chemical Reviews, 2023‏ - ACS Publications
For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …

Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms

Y Zi, K Yang, J He, Z Wu, J Liu, W Zhang - Advanced Drug Delivery …, 2022‏ - Elsevier
Abstract The Enhanced Permeability and Retention (EPR) effect has been recognized as the
central paradigm in tumor-targeted delivery in the last decades. In the wake of this concept …

Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field

X Ma, X Liang, Y Li, Q Feng, K Cheng, N Ma… - Nature …, 2023‏ - nature.com
Micro-nano biorobots based on bacteria have demonstrated great potential for tumor
diagnosis and treatment. The bacterial gene expression and drug release should be …

Exploiting bacteria for cancer immunotherapy

SY Kwon, H Thi-Thu Ngo, J Son, Y Hong… - Nature Reviews Clinical …, 2024‏ - nature.com
Immunotherapy has revolutionized the treatment of cancer but continues to be constrained
by limited response rates, acquired resistance, toxicities and high costs, which necessitates …

Recent progress and trends in X-ray-induced photodynamic therapy with low radiation doses

L He, X Yu, W Li - ACS nano, 2022‏ - ACS Publications
The prominence of photodynamic therapy (PDT) in treating superficial skin cancer inspires
innovative solutions for its congenitally deficient shadow penetration of the visible-light …

Bacteria-cancer interactions: bacteria-based cancer therapy

MTQ Duong, Y Qin, SH You, JJ Min - Experimental & molecular …, 2019‏ - nature.com
Recent advances in cancer therapeutics, such as targeted therapy and immunotherapy,
have raised the hope for cures for many cancer types. However, there are still ongoing …

Tumour-targeting bacteria engineered to fight cancer

S Zhou, C Gravekamp, D Bermudes, K Liu - Nature Reviews Cancer, 2018‏ - nature.com
Recent advances in targeted therapy and immunotherapy have once again raised the hope
that a cure might be within reach for many cancer types. Yet, most late-stage cancers are …

Ultrasound-controllable engineered bacteria for cancer immunotherapy

MH Abedi, MS Yao, DR Mittelstein, A Bar-Zion… - Nature …, 2022‏ - nature.com
Rapid advances in synthetic biology are driving the development of genetically engineered
microbes as therapeutic agents for a multitude of human diseases, including cancer. The …

[PDF][PDF] Bacteria‐based cancer immunotherapy

X Huang, J Pan, F Xu, B Shao, Y Wang… - Advanced …, 2021‏ - Wiley Online Library
In the past decade, bacteria‐based cancer immunotherapy has attracted much attention in
the academic circle due to its unique mechanism and abundant applications in triggering the …

Synchronized cycles of bacterial lysis for in vivo delivery

MO Din, T Danino, A Prindle, M Skalak, J Selimkhanov… - Nature, 2016‏ - nature.com
The widespread view of bacteria as strictly pathogenic has given way to an appreciation of
the prevalence of some beneficial microbes within the human body,,. It is perhaps inevitable …