HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management
Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
Tumor immunology and tumor evolution: intertwined histories
J Galon, D Bruni - Immunity, 2020 - cell.com
Cancer is a complex disease whose outcome depends largely on the cross-talk between the
tumor and its microenvironment. Here, we review the evolution of the field of tumor …
tumor and its microenvironment. Here, we review the evolution of the field of tumor …
Treating head and neck cancer in the age of immunotherapy: a 2023 update
A Bhatia, B Burtness - Drugs, 2023 - Springer
Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …
present with locally advanced disease, requiring multimodality therapy. While this approach …
Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers
K Kataoka, Y Shiraishi, Y Takeda, S Sakata… - Nature, 2016 - nature.com
Successful treatment of many patients with advanced cancer using antibodies against
programmed cell death 1 (PD-1; also known as PDCD1) and its ligand (PD-L1; also known …
programmed cell death 1 (PD-1; also known as PDCD1) and its ligand (PD-L1; also known …
[HTML][HTML] Human papillomavirus-related oropharyngeal cancer
High-risk human papillomavirus (HPV) is now recognised as the principal cause of the
increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some …
increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some …
Mucosal and cutaneous human papillomavirus infections and cancer biology
T Gheit - Frontiers in Oncology, 2019 - frontiersin.org
Papillomaviridae is a family of small non-enveloped icosahedral viruses with double-
stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been …
stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been …
The role of integration in oncogenic progression of HPV-associated cancers
AA McBride, A Warburton - PLoS pathogens, 2017 - journals.plos.org
Persistent infection with a subset of “high oncogenic risk” human papillomaviruses (HPVs)
can promote the development of cancer. In these cancers, the extrachromosomal viral …
can promote the development of cancer. In these cancers, the extrachromosomal viral …
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
L Zhou, Q Qiu, Q Zhou, J Li, M Yu, K Li, L Xu… - Nature …, 2022 - nature.com
Integration of human papillomavirus (HPV) DNA into the human genome is considered as a
key event in cervical carcinogenesis. Here, we perform comprehensive characterization of …
key event in cervical carcinogenesis. Here, we perform comprehensive characterization of …
SvABA: genome-wide detection of structural variants and indels by local assembly
JA Wala, P Bandopadhayay, NF Greenwald… - Genome …, 2018 - genome.cshlp.org
Structural variants (SVs), including small insertion and deletion variants (indels), are
challenging to detect through standard alignment-based variant calling methods. Sequence …
challenging to detect through standard alignment-based variant calling methods. Sequence …
Oropharyngeal carcinoma with a special focus on HPV-related squamous cell carcinoma
Human papillomavirus–positive oropharyngeal squamous cell carcinoma (HPV-OPSCC)
has one of the most rapidly increasing incidences of any cancer in high-income countries …
has one of the most rapidly increasing incidences of any cancer in high-income countries …