The molecular mechanisms of ginkgo (Ginkgo biloba) activity in signaling pathways: A comprehensive review

AM Zonouz, MG Rahbardar, H Hosseinzadeh - Phytomedicine, 2024 - Elsevier
Background One of the most unique plants that have ever grown on the planet is Ginkgo
biloba L., a member of the Ginkgoaceae family with no close living relatives. The existence …

Geraniol attenuates behavioral and neurochemical impairments by inhibitions of HPA-axis and oxido-inflammatory perturbations in mice exposed to post-traumatic …

B Ben-Azu, OG Adebayo, EG Moke… - Journal of Psychiatric …, 2023 - Elsevier
Geraniol is an acyclic isoprenoid monoterpenoid analogue that has been shown to elicit
neuroprotective functions, primarily through its ability to stimulate antioxidant and anti …

Normalization of HPA axis, cholinergic neurotransmission, and inhibiting brain oxidative and inflammatory dynamics are associated with the adaptogenic-like effect of …

JOT Emudainohwo, B Ben-Azu, OG Adebayo… - Journal of Molecular …, 2023 - Springer
Social defeat stress (SDS) due to changes in biochemical functions has been implicated in
the pathogenesis of affective and cognitive disorders. Employing pharmacological approach …

Nano-mediated Management of Metal Toxicity-induced Neurodegeneration: A Critical Review

PR Dubey, G Kaur, R Shukla - Molecular Neurobiology, 2025 - Springer
Heavy metals, omnipresent in the environment, though imperative in trace quantities for
human physiology, become a serious health hazard due to their toxicity. Copper, arsenic …

Ginkgo biloba protects striatal neurodegeneration and gut phagoinflammatory damage in rotenone‐induced mice model of Parkinson's disease: Role of executioner …

OG Adebayo, JN Asiwe, B Ben‐Azu… - Journal of Food …, 2022 - Wiley Online Library
Asymptomatic and early clinical stages of Parkinson's disease (PD) have been linked with
comorbid non‐motor symptoms including dysfunction of the gastrointestinal (GI) tract …

5, 7-dihydroxy-3′, 4′, 5′-trimethoxyflavone mitigates lead induced neurotoxicity in rats via its chelating, antioxidant, anti-inflammatory and monoaminergic …

V Singh, R Shri, P Sood, M Singh, TG Singh… - Food and Chemical …, 2024 - Elsevier
Chronic exposure to lead (Pb) induces neurodegenerative changes in animals and humans.
Drugs with strong antioxidant properties are effective against Pb-mediated neurotoxicity. In a …

[HTML][HTML] 3-hydroxy-3′, 4′, 5′-trimethoxyflavone protects rats against lead-induced neurotoxicity via chelation and modulating oxidative stress, inflammatory and …

V Singh, R Shri, P Sood, M Singh, TG Singh… - Journal of Functional …, 2024 - Elsevier
Lead (Pb) is known to cause neurological changes, but antioxidants, chelators, and anti-
inflammatory agents mitigates Pb toxicity. Previously, we reported antioxidant and anti …

[HTML][HTML] Chronic intermittent oxygen deprivation alters hippocampal cholinergic and glutamatergic system via oxido-inflammatory burden and HIF-1a/Bcl-2 activity in …

OG Adebayo, CI Otene, MU Emmanuel, FC Onwuka… - Phytomedicine Plus, 2023 - Elsevier
Background Several investigations in recent years have reported a relationship between
hypothyroidism or ischemia and central nervous system (CNS) beginning from fetal to adult …

Prenatal double-hit with aluminium and cadmium mediate testicular atrophy and hypothalamic hypoplasia: the role of oxido-nitrergic stress and endocrine …

E Okhue, HE Kadiri, PC Ichipi-Ifukor, B Ben-Azu… - Biometals, 2024 - Springer
There is limited experimental evidence on the biochemical consequences of aluminium (Al)
and cadmium (Cd) co-exposures during pregnancy and postnatal life. This study …