European intersocietal recommendations for the biomarker-based diagnosis of neurocognitive disorders
The recent commercialisation of the first disease-modifying drugs for Alzheimer's disease
emphasises the need for consensus recommendations on the rational use of biomarkers to …
emphasises the need for consensus recommendations on the rational use of biomarkers to …
Nuclear medicine and molecular imaging advances in the 21st century
Currently, Nuclear Medicine has a clearly defined role in clinical practice due to its
usefulness in many medical disciplines. It provides relevant diagnostic and therapeutic …
usefulness in many medical disciplines. It provides relevant diagnostic and therapeutic …
EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3
The present procedural guidelines summarize the current views of the EANM Neuro-
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …
EANM practice guideline for quantitative SPECT-CT
Abstract Purpose Quantitative SPECT-CT is a modality of growing importance with initial
developments in post radionuclide therapy dosimetry, and more recent expansion into bone …
developments in post radionuclide therapy dosimetry, and more recent expansion into bone …
Accurate detection of α‐synuclein seeds in cerebrospinal fluid from isolated rapid eye movement sleep behavior disorder and patients with Parkinson's disease in the …
L Concha‐Marambio, S Weber, CM Farris… - movement …, 2023 - Wiley Online Library
Background Misfolded α‐synuclein (αSyn) aggregates (αSyn‐seeds) in cerebrospinal fluid
(CSF) are biomarkers for synucleinopathies such as Parkinson's disease (PD). αSyn‐seeds …
(CSF) are biomarkers for synucleinopathies such as Parkinson's disease (PD). αSyn‐seeds …
Misfolded α-synuclein assessment in the skin and CSF by RT-QuIC in isolated REM sleep behavior disorder
A Iranzo, A Mammana, A Muñoz-Lopetegi… - Neurology, 2023 - AAN Enterprises
Background and Objectives Real-time quaking-induced conversion (RT-QuIC) assay detects
misfolded α-synuclein (AS) in the skin and CSF of patients with the synucleinopathies …
misfolded α-synuclein (AS) in the skin and CSF of patients with the synucleinopathies …
Loss of presynaptic terminal integrity in the substantia nigra in early Parkinson's disease
Background It has been hypothesized that the pathology of Parkinson's disease (PD)
primarily affects presynaptic terminals and spreads trans‐synaptically. Objectives The main …
primarily affects presynaptic terminals and spreads trans‐synaptically. Objectives The main …
A systematic review of the potential effects of medications and drugs of abuse on dopamine transporter imaging using [123I]I-FP-CIT SPECT in routine practice
Y Chahid, ZH Sheikh, M Mitropoulos, J Booij - European journal of nuclear …, 2023 - Springer
Purpose In routine practice, dopamine transporter (DAT) imaging is frequently used as a
diagnostic tool to support the diagnosis of Parkinson's disease or dementia with Lewy …
diagnostic tool to support the diagnosis of Parkinson's disease or dementia with Lewy …
Brain SPECT as a biomarker of neurodegeneration in dementia in the era of molecular imaging: still a valid option?
R Ferrando, A Damian - Frontiers in Neurology, 2021 - frontiersin.org
Biomarkers are playing a progressively leading role in both clinical practice and scientific
research in dementia. Although amyloid and tau biomarkers have gained ground in the …
research in dementia. Although amyloid and tau biomarkers have gained ground in the …
Different z-score cut-offs for striatal binding ratio (SBR) of DaT SPECT are needed to support the diagnosis of Parkinson's disease (PD) and dementia with Lewy …
Purpose A cut-off of-2 z-score for striatal or putaminal SBR has been to date arbitrarily used
to define an abnormal DaT SPECT in patients with suspected neurodegenerative …
to define an abnormal DaT SPECT in patients with suspected neurodegenerative …