The recent commercialisation of the first disease-modifying drugs for Alzheimer's disease
emphasises the need for consensus recommendations on the rational use of biomarkers to …

Currently, Nuclear Medicine has a clearly defined role in clinical practice due to its
usefulness in many medical disciplines. It provides relevant diagnostic and therapeutic …

The present procedural guidelines summarize the current views of the EANM Neuro-
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …

Abstract Purpose Quantitative SPECT-CT is a modality of growing importance with initial
developments in post radionuclide therapy dosimetry, and more recent expansion into bone …

Background Misfolded α‐synuclein (αSyn) aggregates (αSyn‐seeds) in cerebrospinal fluid
(CSF) are biomarkers for synucleinopathies such as Parkinson's disease (PD). αSyn‐seeds …

Background and Objectives Real-time quaking-induced conversion (RT-QuIC) assay detects
misfolded α-synuclein (AS) in the skin and CSF of patients with the synucleinopathies …

Objective To apply a machine learning analysis to clinical and presynaptic dopaminergic
imaging data of patients with rapid eye movement (REM) sleep behavior disorder (RBD) to …

Background It has been hypothesized that the pathology of Parkinson's disease (PD)
primarily affects presynaptic terminals and spreads trans‐synaptically. Objectives The main …

Biomarkers are playing a progressively leading role in both clinical practice and scientific
research in dementia. Although amyloid and tau biomarkers have gained ground in the …

A major goal of current clinical research in Parkinson's disease (PD) is the validation and
standardization of biomarkers enabling early diagnosis, predicting outcomes, understanding …