Integrating CRISPR/Cas within isothermal amplification for point-of-Care Assay of nucleic acid
L Zhang, H Jiang, Z Zhu, J Liu, B Li - Talanta, 2022 - Elsevier
Nucleic acid detection technology is now widely used in scientific research and clinical
testing, such as infectious and genetic diseases screening, molecular diagnosis of tumors …
testing, such as infectious and genetic diseases screening, molecular diagnosis of tumors …
CRISPR-based biosensors for pathogenic biosafety
H Yang, R Ledesma-Amaro, H Gao, Y Ren… - Biosensors and …, 2023 - Elsevier
Pathogenic biosafety is a worldwide concern. Tools for analyzing pathogenic biosafety, that
are precise, rapid and field-deployable, are highly demanded. Recently developed …
are precise, rapid and field-deployable, are highly demanded. Recently developed …
Uniform stain pattern of robust MOF-mediated probe for flexible paper-based colorimetric sensing toward environmental pesticide exposure
X Zhang, Z Wang, X Huang, Q Huang, Y Wen… - Chemical Engineering …, 2023 - Elsevier
Excessive residual pesticides have raised overall environmental damage and health hazard
issues, thus the development of facile and sensitive means for pesticide monitoring in …
issues, thus the development of facile and sensitive means for pesticide monitoring in …
Pyrococcus furiosus Argonaute Combined with Recombinase Polymerase Amplification for Rapid and Sensitive Detection of Enterocytozoon hepatopenaei
L Yang, B Guo, Y Wang, C Zhao, X Zhang… - Journal of Agricultural …, 2022 - ACS Publications
Enterocytozoon hepatopenaei (EHP) is one of the most serious pathogens in shrimp
farming. This study combines recombinase polymerase amplification (RPA) with the …
farming. This study combines recombinase polymerase amplification (RPA) with the …
CRISPR-based biosensors for human health: A novel strategy to detect emerging infectious diseases
Infectious diseases (such as sepsis, influenza, and malaria), caused by various pathogenic
bacteria and viruses, are widespread across the world. Early and rapid detection of disease …
bacteria and viruses, are widespread across the world. Early and rapid detection of disease …
One-pot molecular diagnosis of acute hepatopancreatic necrosis disease by recombinase polymerase amplification and CRISPR/Cas12a with specially designed …
P Wang, B Guo, X Zhang, Y Wang, G Yang… - Journal of Agricultural …, 2023 - ACS Publications
Acute hepatopancreatic necrosis disease (AHPND) is one of the most devastating diseases
in aquaculture, causing significant economic losses in seafood supplies worldwide. Early …
in aquaculture, causing significant economic losses in seafood supplies worldwide. Early …
CRISPR/Cas-based diagnostics in agricultural applications
Pests and disease-causing pathogens frequently impede agricultural production. An early
and efficient diagnostic tool is crucial for effective disease management. Clustered regularly …
and efficient diagnostic tool is crucial for effective disease management. Clustered regularly …
Recent Progress in Molecular Diagnostics: The Synergy of Rolling Circle Amplification and CRISPR/Cas Systems (2018-2024)–A Concise Review
Z Zhu, L Yang - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Abstract The fusion of Rolling Circle Amplification (RCA) and the Clustered Regularly
Interspaced Short Palindromic Repeats–CRISPR-associated proteins (CRISPR-Cas) stands …
Interspaced Short Palindromic Repeats–CRISPR-associated proteins (CRISPR-Cas) stands …
Csm6-DNAzyme tandem assay for one-pot and sensitive analysis of lead pollution and bioaccumulation in mice
Lead contamination in the environment tends to enter the food chain and further into the
human body, causing serious health issues. Herein, we proposed a Csm6-DNAzyme …
human body, causing serious health issues. Herein, we proposed a Csm6-DNAzyme …
Rapid in situ RNA imaging based on Cas12a thrusting strand displacement reaction
X Cheng, X Li, Y Kang, D Zhang, Q Yu… - Nucleic Acids …, 2023 - academic.oup.com
RNA In situ imaging through DNA self-assembly is advantaged in illustrating its structures
and functions with high-resolution, while the limited reaction efficiency and time-consuming …
and functions with high-resolution, while the limited reaction efficiency and time-consuming …