The genome sequence of Mycobacterium tuberculosis strain H37Rv is an important and
valuable reference point in the study of M. tuberculosis phylogeny, molecular epidemiology …

Introduction Around 10% of the coding potential of Mycobacterium tuberculosis is constituted
by two poorly understood gene families, the pe and ppe loci, thought to be involved in host …

With> 1 million associated deaths in 2020, human tuberculosis (TB) caused by the bacteria
Mycobacterium tuberculosis remains one of the deadliest infectious diseases. A plethora of …

A better understanding of the genomic changes that facilitate the emergence and spread of
drug-resistant Mycobacterium tuberculosis strains is currently required. Here, we report the …

Mycobacterium tuberculosis, a Gram-positive bacterium of great clinical relevance, is a
lethal pathogen owing to its complex physiological characteristics and development of drug …

This study assembles DNA adenine methylomes for 93 Mycobacterium tuberculosis
complex (MTBC) isolates from seven lineages paired with fully-annotated, finished, de novo …

Accurate and timely functional genome annotation is essential for translating basic pathogen
research into clinically impactful advances. Here, through literature curation and structure …

Point mutations in the rrs gene and the eis promoter are known to confer resistance to the
second-line injectable drugs (SLIDs) amikacin (AMK), capreomycin (CAP), and kanamycin …

H37Ra is a virulence attenuated strain of Mycobacterium tuberculosis widely employed as a
model to investigate virulence mechanisms. Comparative high-throughput studies have …

Long‐read sequencing is a valuable technique for high‐precision genome analysis. Despite
the widespread use of the Mycobacterium tuberculosis H37Rv genome sequence as a …