The chemistry of nitrogen-centered radicals (NCRs) has plentiful applications in organic
synthesis, and they continue to expand as our understanding of these reactive species …

The development of late-stage functionalization (LSF) methodologies, particularly C–H
functionalization, has revolutionized the field of organic synthesis. Over the past decade …

Radical/radical cross-coupling reactions represent an efficient and straightforward approach
for the construction of chemical bonds and accordingly have drawn increasing attention over …

Redox processes are at the heart of synthetic methods that rely on either electrochemistry or
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …

In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science
industry require access to mild and robust synthetic methodologies to systematically modify …

We present here a review of the photochemical and electrochemical applications of multi-
site proton-coupled electron transfer (MS-PCET) in organic synthesis. MS-PCETs are redox …

Late-stage functionalization of C–H bonds (C–H LSF) can provide a straightforward
approach to the efficient synthesis of functionalized complex molecules. However, C–H LSF …

Since its inception, atom transfer radical polymerization (ATRP) has seen continuous
evolution in terms of the design of the catalyst and reaction conditions; today, it is one of the …

The polarity of a radical intermediate profoundly impacts its reactivity and selectivity. To
quantify this influence and predict its effects, the electrophilicity/nucleophilicity of> 500 …

As the largest renewable carbon resource, lignocellulosic biomass has great potential to
replace fossil resources for the production of high-value chemicals, in particular organic …