Background: Endometriosis affects more than 10% of reproductive-aged women, causing
pelvic pain and infertility. Despite the benign nature of endometriosis, ovarian …

Although the histologic diagnosis of endometriosis is usually straightforward, many
diagnostic problems can arise as a result of alterations or absence of its glandular or stromal …

Hereditary ovarian cancer accounts for at least 5% of the estimated 22,000 new cases of this
disease during 2009. During this same time, over 15,000 will die from malignancy ascribed …

Endometriosis is a chronic disease that affects millions of reproductive-age women. Despite
the destructive and invasive nature of endometrioses, most cases are perpetually benign or …

BACKGROUND Endometriosis is a benign gynaecological disease. Thus, it came as a
complete surprise when it was reported recently that the majority of deep endometriosis …

Objectives ARID1A is a recently identif ied tumor suppressor participating in chromatin
remodeling. Somatic inactivating mutations of ARID1A and loss of its expression occur …

The ultimate goal of defining cancer specific precursors is to facilitate early detection and
intervention before the development of invasive malignancy. Unlike other malignancies …

Endometriosis is a fascinating disease that we strive to better understand. Molecular
techniques are shedding new light on many important aspects of this disease: from …

Recent molecular and pathological evidence suggests that endometriosis is a monoclonal,
neoplastic disease. Moreover, endometriosis serves as a precursor of ovarian cancer …

Clear cell carcinoma of the ovary is a distinct histological subtype of epithelial ovarian
cancer characterized by mutations in ARID1A and PIK3CA. These malignancies account for …