Elucidating the structure and interactions of proteins in native environments is a fundamental
goal of structural biology. Nuclear magnetic resonance (NMR) spectroscopy is well suited for …

Membrane proteins play crucial roles in cellular signal transduction, molecule transport, host-
pathogen interactions, and metabolic processes. However, mutations, changes in …

The low sensitivity of nuclear magnetic resonance (NMR) is a major bottleneck for studying
biomolecular structures of complex biomolecular assemblies. Cryogenically cooled probe …

Dynamic nuclear polarization (DNP) is a powerful tool to enhance the NMR signals of
molecules by transferring polarization from unpaired electron spins to nuclei through …

Plague caused by Yersinia pestis remains a public health threat worldwide. Because
multidrug-resistant Y. pestis strains have been found in both humans and animals, phage …

Yersinia pestis, the causative agent of plague, is capable of evading the human immune
system response by recruiting the plasma circulating vitronectin proteins, which act as a …

The outer membrane vesicles (OMVs) produced by diderm bacteria have important roles in
cell envelope homeostasis, secretion, interbacterial communication, and pathogenesis. The …

The unique strength of solution-state nuclear magnetic resonance (NMR) is to contribute not
only to determine high-resolution structures of macromolecules but also to provide …

Nature has evolved sophisticated mechanisms of producing biomolecular structures that
compartmentalize various biochemical and cellular environments. Biological membranes …