Effects of selection at linked sites on patterns of genetic variability
B Charlesworth, JD Jensen - Annual review of ecology …, 2021 - annualreviews.org
Patterns of variation and evolution at a given site in a genome can be strongly influenced by
the effects of selection at genetically linked sites. In particular, the recombination rates of …
the effects of selection at genetically linked sites. In particular, the recombination rates of …
Selective sweeps
W Stephan - Genetics, 2019 - academic.oup.com
For almost 20 years, many inference methods have been developed to detect selective
sweeps and localize the targets of directional selection in the genome. These methods are …
sweeps and localize the targets of directional selection in the genome. These methods are …
A model species for agricultural pest genomics: the genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae)
The Colorado potato beetle is one of the most challenging agricultural pests to manage. It
has shown a spectacular ability to adapt to a variety of solanaceaeous plants and variable …
has shown a spectacular ability to adapt to a variety of solanaceaeous plants and variable …
The importance of the neutral theory in 1968 and 50 years on: a response to Kern and Hahn 2018
A recent article reassessing the Neutral Theory of Molecular Evolution claims that it is no
longer as important as is widely believed. The authors argue that “the neutral theory was …
longer as important as is widely believed. The authors argue that “the neutral theory was …
Genome resequencing reveals rapid, repeated evolution in the Colorado potato beetle
Insecticide resistance and rapid pest evolution threatens food security and the development
of sustainable agricultural practices, yet the evolutionary mechanisms that allow pests to …
of sustainable agricultural practices, yet the evolutionary mechanisms that allow pests to …
Toward an evolutionarily appropriate null model: jointly inferring demography and purifying selection
The relative evolutionary roles of adaptive and non-adaptive processes remain a central
question in population genetics. Resolution of this debate has been difficult as an …
question in population genetics. Resolution of this debate has been difficult as an …
How chromosomal inversions reorient the evolutionary process
Inversions are structural mutations that reverse the sequence of a chromosome segment
and reduce the effective rate of recombination in the heterozygous state. They play a major …
and reduce the effective rate of recombination in the heterozygous state. They play a major …
Detecting positive selection in the genome
Population geneticists have long sought to understand the contribution of natural selection
to molecular evolution. A variety of approaches have been proposed that use population …
to molecular evolution. A variety of approaches have been proposed that use population …
The determinants of genetic diversity in butterflies
Under the neutral theory, genetic diversity is expected to increase with population size.
While comparative analyses have consistently failed to find strong relationships between …
While comparative analyses have consistently failed to find strong relationships between …
The impact of purifying and background selection on the inference of population history: problems and prospects
Current procedures for inferring population history generally assume complete neutrality—
that is, they neglect both direct selection and the effects of selection on linked sites. We here …
that is, they neglect both direct selection and the effects of selection on linked sites. We here …