In recent years, microbioreactor (MBR) systems have evolved towards versatile bioprocess
engineering tools. They provide a unique solution to combine higher experimental …

Synthetic biology offers the opportunity to build solutions for improved capture and
conversion of carbon dioxide (CO2) that outcompete those evolved by nature. Here we …

Pharmaceuticals have extensive reciprocal interactions with the microbiome, but whether
bacterial drug sensitivity and metabolism is driven by pathways conserved in host cells …

Serving a robust platform for reverse genetics enabling the in vivo study of gene functions
primarily in enterobacteriaceae, recombineering-or recombination-mediated genetic …

Carbon fixation is one of the most important biochemical processes. Most natural carbon
fixation pathways are thought to have emerged from enzymes that originally performed other …

Formate can be directly produced from CO 2 and renewable electricity, making it a
promising microbial feedstock for sustainable bioproduction. Cupriavidus necator is one of …

Mechanistic insights into the role of the human microbiome in the predisposition to and
treatment of disease are limited by the lack of methods to precisely add or remove microbial …

Anaerobic microbial fermentations provide high product yields and are a cornerstone of
industrial bio-based processes. However, the need for redox balancing limits the array of …

Computational modelling of metabolic networks has become an established procedure in
the metabolic engineering of production strains. One key principle that is frequently used to …

Abstract One-carbon (C1) substrates, such as methanol or formate, are attractive feedstocks
for circular bioeconomy. These substrates are typically converted into formaldehyde, serving …