Radiogenomics: bridging imaging and genomics

Z Bodalal, S Trebeschi, TDL Nguyen-Kim, W Schats… - Abdominal …, 2019 - Springer
From diagnostics to prognosis to response prediction, new applications for radiomics are
rapidly being developed. One of the fastest evolving branches involves linking imaging …

Precision medicine and radiogenomics in breast cancer: new approaches toward diagnosis and treatment

K Pinker, J Chin, AN Melsaether, EA Morris, L Moy - Radiology, 2018 - pubs.rsna.org
Precision medicine is medicine optimized to the genotypic and phenotypic characteristics of
an individual and, when present, his or her disease. It has a host of targets, including genes …

Association of peritumoral radiomics with tumor biology and pathologic response to preoperative targeted therapy for HER2 (ERBB2)–positive breast cancer

N Braman, P Prasanna, J Whitney, S Singh… - JAMA network …, 2019 - jamanetwork.com
Importance There has been significant recent interest in understanding the utility of
quantitative imaging to delineate breast cancer intrinsic biological factors and therapeutic …

Quantitative MRI radiomics in the prediction of molecular classifications of breast cancer subtypes in the TCGA/TCIA data set

H Li, Y Zhu, ES Burnside, E Huang, K Drukker… - NPJ breast …, 2016 - nature.com
Using quantitative radiomics, we demonstrate that computer-extracted magnetic resonance
(MR) image-based tumor phenotypes can be predictive of the molecular classification of …

A machine learning approach to radiogenomics of breast cancer: a study of 922 subjects and 529 DCE-MRI features

A Saha, MR Harowicz, LJ Grimm, CE Kim… - British journal of …, 2018 - nature.com
Background Recent studies showed preliminary data on associations of MRI-based imaging
phenotypes of breast tumours with breast cancer molecular, genomic, and related …

Radiomics signature on magnetic resonance imaging: association with disease-free survival in patients with invasive breast cancer

H Park, Y Lim, ES Ko, H Cho, JE Lee, BK Han… - Clinical Cancer …, 2018 - AACR
Purpose: To develop a radiomics signature based on preoperative MRI to estimate disease-
free survival (DFS) in patients with invasive breast cancer and to establish a radiomics …

Radiogenomics: what it is and why it is important

MA Mazurowski - Journal of the American College of Radiology, 2015 - Elsevier
In recent years, a new direction in cancer research has emerged that focuses on the
relationship between imaging phenotypes and genomics. This direction is referred to as …

The crucial role of multiomic approach in cancer research and clinically relevant outcomes

M Lu, X Zhan - EPMA Journal, 2018 - Springer
Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …

Prostate cancer radiogenomics—from imaging to molecular characterization

M Ferro, O de Cobelli, MD Vartolomei… - International Journal of …, 2021 - mdpi.com
Radiomics and genomics represent two of the most promising fields of cancer research,
designed to improve the risk stratification and disease management of patients with prostate …

Background, current role, and potential applications of radiogenomics

K Pinker, F Shitano, E Sala, RK Do… - Journal of Magnetic …, 2018 - Wiley Online Library
With the genomic revolution in the early 1990s, medical research has been driven to study
the basis of human disease on a genomic level and to devise precise cancer therapies …