Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Copper signalling: causes and consequences

J Kardos, L Héja, Á Simon, I Jablonkai… - Cell Communication and …, 2018 - Springer
Copper-containing enzymes perform fundamental functions by activating dioxygen (O 2) and
therefore allowing chemical energy-transfer for aerobic metabolism. The copper …

Anticancer potency of copper (II) complexes of thiosemicarbazones

NK Singh, AA Kumbhar, YR Pokharel… - Journal of Inorganic …, 2020 - Elsevier
Being a structural and catalytic cofactor in a number of biological pathways, copper
accumulates in tumors owing to selective permeability of the cancer cell membranes …

Copper complexes as therapeutic agents

C Duncan, AR White - Metallomics, 2012 - academic.oup.com
The importance of transition metals in biological processes has been well established.
Copper (Cu) is a transition metal that can exist in oxidised and reduced states. This allows it …

Ni (II) and Cu (II) complexes with ONNO asymmetric tetradentate Schiff base ligand: synthesis, spectroscopic characterization, theoretical calculations, DNA interaction …

LH Abdel‐Rahman, AM Abu‐Dief… - Applied …, 2017 - Wiley Online Library
A novel Schiff base, namely Z‐3‐((2‐((E)‐(2‐hydroxynaphthyl) methylene) amino)‐5‐
nitrophenylimino)‐1, 3‐dihydroindin‐2‐one, was synthesized from the condensation of 2 …

Advances in chromone-based copper (ii) Schiff base complexes: synthesis, characterization, and versatile applications in pharmacology and biomimetic catalysis

S Kumar, A Arora, VK Maikhuri, A Chaudhary… - RSC …, 2024 - pubs.rsc.org
Chromones are well known as fundamental structural elements found in numerous natural
compounds and medicinal substances. The Schiff bases of chromones have a much wider …

Copper Complexes as Antitumor Agents: In vitro and In vivo Evidence

LM Balsa, EJ Baran, IE León - Current medicinal chemistry, 2023 - benthamdirect.com
Copper is an essential element for most aerobic organisms, with an important function as a
structural and catalytic cofactor, and in consequence, it is implicated in several biological …

Development of copper based drugs, radiopharmaceuticals and medical materials

P Szymański, T Frączek, M Markowicz… - Biometals, 2012 - Springer
Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …

Synthesis, spectroscopic characterization, biological screening and in vitro cytotoxic studies of 4‐methyl‐3‐thiosemicarbazone derived Schiff bases and their Co (II) …

J Devi, M Yadav, DK **dal, D Kumar… - Applied …, 2019 - Wiley Online Library
A series of twenty compounds inclusive of bidentate Schiff bases derived from condensation
of 4‐methyl‐3‐thiosemicarbazide with substituted derivatives of napthaldehyde …

Synthesis, characterization, spectral studies two new transition metal complexes derived from pyrazolone by theoretical studies, and investigate anti‐proliferative …

S Parvarinezhad, M Salehi… - Applied …, 2022 - Wiley Online Library
Metal (II) complexes of Cu (II)(1), and Ni (II)(2) with Schiff base derived from 4‐amino‐
antipyrine were synthesized. These complexes were fully characterized by FTIR, and UV …