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Advances in copper complexes as anticancer agents
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …
Copper signalling: causes and consequences
Copper-containing enzymes perform fundamental functions by activating dioxygen (O 2) and
therefore allowing chemical energy-transfer for aerobic metabolism. The copper …
therefore allowing chemical energy-transfer for aerobic metabolism. The copper …
Anticancer potency of copper (II) complexes of thiosemicarbazones
Being a structural and catalytic cofactor in a number of biological pathways, copper
accumulates in tumors owing to selective permeability of the cancer cell membranes …
accumulates in tumors owing to selective permeability of the cancer cell membranes …
Copper complexes as therapeutic agents
C Duncan, AR White - Metallomics, 2012 - academic.oup.com
The importance of transition metals in biological processes has been well established.
Copper (Cu) is a transition metal that can exist in oxidised and reduced states. This allows it …
Copper (Cu) is a transition metal that can exist in oxidised and reduced states. This allows it …
Ni (II) and Cu (II) complexes with ONNO asymmetric tetradentate Schiff base ligand: synthesis, spectroscopic characterization, theoretical calculations, DNA interaction …
LH Abdel‐Rahman, AM Abu‐Dief… - Applied …, 2017 - Wiley Online Library
A novel Schiff base, namely Z‐3‐((2‐((E)‐(2‐hydroxynaphthyl) methylene) amino)‐5‐
nitrophenylimino)‐1, 3‐dihydroindin‐2‐one, was synthesized from the condensation of 2 …
nitrophenylimino)‐1, 3‐dihydroindin‐2‐one, was synthesized from the condensation of 2 …
Advances in chromone-based copper (ii) Schiff base complexes: synthesis, characterization, and versatile applications in pharmacology and biomimetic catalysis
Chromones are well known as fundamental structural elements found in numerous natural
compounds and medicinal substances. The Schiff bases of chromones have a much wider …
compounds and medicinal substances. The Schiff bases of chromones have a much wider …
Copper Complexes as Antitumor Agents: In vitro and In vivo Evidence
Copper is an essential element for most aerobic organisms, with an important function as a
structural and catalytic cofactor, and in consequence, it is implicated in several biological …
structural and catalytic cofactor, and in consequence, it is implicated in several biological …
Development of copper based drugs, radiopharmaceuticals and medical materials
P Szymański, T Frączek, M Markowicz… - Biometals, 2012 - Springer
Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …
compounds show vast array of biological actions, including anti-inflammatory, anti …
Synthesis, spectroscopic characterization, biological screening and in vitro cytotoxic studies of 4‐methyl‐3‐thiosemicarbazone derived Schiff bases and their Co (II) …
A series of twenty compounds inclusive of bidentate Schiff bases derived from condensation
of 4‐methyl‐3‐thiosemicarbazide with substituted derivatives of napthaldehyde …
of 4‐methyl‐3‐thiosemicarbazide with substituted derivatives of napthaldehyde …
Synthesis, characterization, spectral studies two new transition metal complexes derived from pyrazolone by theoretical studies, and investigate anti‐proliferative …
Metal (II) complexes of Cu (II)(1), and Ni (II)(2) with Schiff base derived from 4‐amino‐
antipyrine were synthesized. These complexes were fully characterized by FTIR, and UV …
antipyrine were synthesized. These complexes were fully characterized by FTIR, and UV …