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Identifying miRNAs, targets and functions
Abstract microRNAs (miRNAs) are small endogenous non-coding RNAs that function as the
universal specificity factors in post-transcriptional gene silencing. Discovering miRNAs …
universal specificity factors in post-transcriptional gene silencing. Discovering miRNAs …
Non-coding RNAs and their roles in stress response in plants
Eukaryotic genomes encode thousands of non-coding RNAs (ncRNAs), which play crucial
roles in transcriptional and post-transcriptional regulation of gene expression. Accumulating …
roles in transcriptional and post-transcriptional regulation of gene expression. Accumulating …
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
Abstract microRNAs (miRNAs) are a large class of small non-coding RNAs which post-
transcriptionally regulate the expression of a large fraction of all animal genes and are …
transcriptionally regulate the expression of a large fraction of all animal genes and are …
miRDeepFinder: a miRNA analysis tool for deep sequencing of plant small RNAs
Abstract miRDeepFinder is a software package developed to identify and functionally
analyze plant microRNAs (miRNAs) and their targets from small RNA datasets obtained from …
analyze plant microRNAs (miRNAs) and their targets from small RNA datasets obtained from …
Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support
KC Yang, KA Yamada, AY Patel, VK Topkara… - Circulation, 2014 - ahajournals.org
Background—Microarrays have been used extensively to profile transcriptome remodeling
in failing human heart, although the genomic coverage provided is limited and fails to …
in failing human heart, although the genomic coverage provided is limited and fails to …
miREvo: an integrative microRNA evolutionary analysis platform for next-generation sequencing experiments
Background MicroRNAs (miRNAs) are small (~ 19-24nt) non-coding RNAs that play
important roles in various biological processes. To date, the next-generation sequencing …
important roles in various biological processes. To date, the next-generation sequencing …
Evidence for natural antisense transcript-mediated inhibition of microRNA function
Background MicroRNAs (miRNAs) have the potential to regulate diverse sets of mRNA
targets. In addition, mammalian genomes contain numerous natural antisense transcripts …
targets. In addition, mammalian genomes contain numerous natural antisense transcripts …
Bioinformatic tools for microRNA dissection
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
Diverse human extracellular RNAs are widely detected in human plasma
There is growing appreciation for the importance of non-protein-coding genes in
development and disease. Although much is known about microRNAs, limitations in …
development and disease. Although much is known about microRNAs, limitations in …
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression
Platelets play a crucial role in the pathogenesis of myocardial infarction (MI) by adhering to
the site of a ruptured atherosclerotic plaque. The aim of this study was to screen for …
the site of a ruptured atherosclerotic plaque. The aim of this study was to screen for …