Polarizing agents for efficient high field DNP solid-state NMR spectroscopy under magic-angle spinning: from design principles to formulation strategies

G Menzildjian, J Schlagnitweit, G Casano, O Ouari… - Chemical …, 2023 - pubs.rsc.org
Dynamic Nuclear Polarization (DNP) has recently emerged as a cornerstone approach to
enhance the sensitivity of solid-state NMR spectroscopy under Magic Angle Spinning (MAS) …

Role of electron spin dynamics and coupling network in designing dynamic nuclear polarization

A Equbal, SK Jain, Y Li, K Tagami, X Wang… - Progress in Nuclear …, 2021 - Elsevier
Dynamic nuclear polarization (DNP) has emerged as a powerful sensitivity booster of
nuclear magnetic resonance (NMR) spectroscopy for the characterization of biological …

P1 center electron spin clusters are prevalent in type Ib diamonds

S Bussandri, D Shimon, A Equbal, Y Ren… - Journal of the …, 2023 - ACS Publications
Understanding the spatial distribution of the P1 centers is crucial for diamond-based sensors
and quantum devices. P1 centers serve as polarization sources for dynamic nuclear …

Rational design of dinitroxide polarizing agents for dynamic nuclear polarization to enhance overall NMR sensitivity

A Venkatesh, G Casano, R Wei, Y Rao… - Angewandte Chemie …, 2024 - Wiley Online Library
We evaluate the overall sensitivity gains provided by a series of eighteen nitroxide biradicals
for dynamic nuclear polarization (DNP) solid‐state NMR at 9.4 T and 100 K, including eight …

Open and closed radicals: local geometry around unpaired electrons governs magic-angle spinning dynamic nuclear polarization performance

G Stevanato, G Casano, DJ Kubicki… - Journal of the …, 2020 - ACS Publications
The development of magic-angle spinning dynamic nuclear polarization (MAS DNP) has
allowed atomic-level characterization of materials for which conventional solid-state NMR is …

Role of protons in and around strongly coupled nitroxide biradicals for cross-effect dynamic nuclear polarization

S Chatterjee, A Venkatesh, ST Sigurdsson… - The Journal of …, 2024 - ACS Publications
In magic angle spinning dynamic nuclear polarization (DNP), biradicals such as bis-
nitroxides are used to hyperpolarize protons under microwave irradiation through the cross …

PyrroTriPol: a semi-rigid trityl-nitroxide for high field dynamic nuclear polarization

T Halbritter, R Harrabi, S Paul, J van Tol, D Lee… - Chemical …, 2023 - pubs.rsc.org
Magic angle spinning (MAS) dynamic nuclear polarization (DNP) has significantly
broadened the scope of solid-state NMR to study biomolecular systems and materials. In …

Postmodification via thiol-click chemistry yields hydrophilic trityl-nitroxide biradicals for biomolecular high-field dynamic nuclear polarization

W Zhai, A Lucini Paioni, X Cai… - The Journal of …, 2020 - ACS Publications
Dynamic nuclear polarization (DNP) is a powerful method to enhance nuclear magnetic
resonance (NMR) signal intensities, enabling unprecedented applications in life and …

Large cross-effect dynamic nuclear polarisation enhancements with kilowatt inverting chirped pulses at 94 GHz

Y Zhao, H El Mkami, RI Hunter, G Casano… - Communications …, 2023 - nature.com
Dynamic nuclear polarisation (DNP) is a process that transfers electron spin polarisation to
nuclei by applying resonant microwave radiation, and has been widely used to improve the …

[HTML][HTML] A primer to polarizing agent design: Quantum mechanical understanding of cross effect magic-angle spinning Dynamic Nuclear Polarization

L Gkoura, A Equbal - Journal of Magnetic Resonance Open, 2023 - Elsevier
Abstract Dynamic Nuclear Polarization (DNP) is transforming the landscape of solid-state
characterization for both biological solids and functional materials. By transferring electron …