Creatine is one of the most popular nutritional ergogenic aids for athletes. Studies have
consistently shown that creatine supplementation increases intramuscular creatine …

Although creatine has been mostly studied as an ergogenic aid for exercise, training, and
sport, several health and potential therapeutic benefits have been reported. This is because …

Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

The term mitochondrial permeability transition (MPT) is commonly used to indicate an abrupt
increase in the permeability of the inner mitochondrial membrane to low molecular weight …

The pleiotropic effects of creatine (Cr) are based mostly on the functions of the enzyme
creatine kinase (CK) and its high-energy product phosphocreatine (PCr). Multidisciplinary …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

Mitochondrial creatine kinase (MtCK), together with cytosolic creatine kinase isoenzymes
and the highly diffusible CK reaction product, phosphocreatine, provide a temporal and …

Creatine has become a popular nutritional supplement among athletes. Recent research
has also suggested that there may be a number of potential therapeutic uses of creatine …

The requirement of chemical energy in the form of ATP to support systolic and diastolic work
of the heart is absolute. Because of its central role in cardiac metabolism and performance …

▪ Abstract Phosphagens are phosphorylated guanidino compounds that are linked to energy
state and ATP hydrolysis by corresponding phosphagen kinase reactions: phosphagen+ …