Inflammasomes are critical sentinels of the innate immune system that respond to threats to
the host through recognition of distinct molecules, known as pathogen-or damage …

Myeloperoxidase (MPO) belongs to the heme peroxidase family, which includes a set of
enzymes with potent oxidoreductase activity. MPO is considered an important part of the …

The Mediterranean diet is considered as the foremost dietary regimen and its adoption is
associated with the prevention of degenerative diseases and an extended longevity. The …

Multiple factors are involved in the etiology of cardiovascular disease (CVD). Pathological
changes occur in a variety of cell types long before symptoms become apparent and …

Based on the “free radical theory” of disease, researchers have been trying to elucidate the
role of oxidative stress from free radicals in cardiovascular disease. Considerable data …

Atherosclerosis is a life-long illness that begins with risk factors, which in turn contribute to
the development of subclinical disease, followed by the establishment of overt …

Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this
property accounts for all its known functions. As an electron donor, vitamin C is a potent …

The inflammasome is a cytoplasmic protein complex that processes interleukins (IL)-1β and
IL-18, and drives a form of cell death known as pyroptosis. Oligomerization of this complex is …

Metabolic syndrome is a collection of cardiometabolic risk factors that includes obesity,
insulin resistance, hypertension and dyslipidemia. Although there has been significant …

Background Lp (a) lipoprotein binds proinflammatory oxidized phospholipids. We
investigated whether levels of oxidized low-density lipoprotein (LDL) measured with use of …