Big data and artificial intelligence in cancer research

X Wu, W Li, H Tu - Trends in cancer, 2024 - cell.com
The field of oncology has witnessed an extraordinary surge in the application of big data and
artificial intelligence (AI). AI development has made multiscale and multimodal data fusion …

A systematic analysis of deep learning in genomics and histopathology for precision oncology

M Unger, JN Kather - BMC Medical Genomics, 2024 - Springer
Background Digitized histopathological tissue slides and genomics profiling data are
available for many patients with solid tumors. In the last 5 years, Deep Learning (DL) has …

A pathology foundation model for cancer diagnosis and prognosis prediction

X Wang, J Zhao, E Marostica, W Yuan, J **, J Zhang… - Nature, 2024 - nature.com
Histopathology image evaluation is indispensable for cancer diagnoses and subtype
classification. Standard artificial intelligence methods for histopathology image analyses …

[HTML][HTML] Histopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients

PC Tsai, TH Lee, KC Kuo, FY Su, TLM Lee… - Nature …, 2023 - nature.com
Histopathologic assessment is indispensable for diagnosing colorectal cancer (CRC).
However, manual evaluation of the diseased tissues under the microscope cannot reliably …

Deep learning models for histologic grading of breast cancer and association with disease prognosis

R Jaroensri, E Wulczyn, N Hegde, T Brown… - NPJ Breast …, 2022 - nature.com
Histologic grading of breast cancer involves review and scoring of three well-established
morphologic features: mitotic count, nuclear pleomorphism, and tubule formation. Taken …

The clinical utility of lncRNAs and their application as molecular biomarkers in breast cancer

C Arriaga-Canon, L Contreras-Espinosa… - International Journal of …, 2023 - mdpi.com
Given their tumor-specific and stage-specific gene expression, long non-coding RNAs
(lncRNAs) have demonstrated to be potential molecular biomarkers for diagnosis …

Deep learning artificial intelligence predicts homologous recombination deficiency and platinum response from histologic slides

EN Bergstrom, A Abbasi, M Díaz-Gay… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Cancers with homologous recombination deficiency (HRD) can benefit from
platinum salts and poly (ADP-ribose) polymerase inhibitors. Standard diagnostic tests for …

Machine learning for cryosection pathology predicts the 2021 WHO classification of glioma

MLP Nasrallah, J Zhao, CC Tsai, D Meredith… - Med, 2023 - cell.com
Background Timely and accurate intraoperative cryosection evaluations remain the gold
standard for guiding surgical treatments for gliomas. However, the tissue-freezing process …

Artificial intelligence in breast cancer histopathology

RCK Chan, CKC To, KCT Cheng, T Yoshikazu… - …, 2023 - Wiley Online Library
This is a review on the use of artificial intelligence for digital breast pathology. A systematic
search on PubMed was conducted, identifying 17,324 research papers related to breast …

[HTML][HTML] Deep learning-based prediction of molecular tumor biomarkers from H&E: A practical review

HD Couture - Journal of Personalized Medicine, 2022 - mdpi.com
Molecular and genomic properties are critical in selecting cancer treatments to target
individual tumors, particularly for immunotherapy. However, the methods to assess such …