The biology and mathematical modelling of glioma invasion: a review

JCL Alfonso, K Talkenberger… - Journal of the …, 2017‏ - royalsocietypublishing.org
Adult gliomas are aggressive brain tumours associated with low patient survival rates and
limited life expectancy. The most important hallmark of this type of tumour is its invasive …

Cellular potts modeling of tumor growth, tumor invasion, and tumor evolution

A Szabó, RMH Merks - Frontiers in oncology, 2013‏ - frontiersin.org
Despite a growing wealth of available molecular data, the growth of tumors, invasion of
tumors into healthy tissue, and response of tumors to therapies are still poorly understood …

Nonlinear modelling of cancer: bridging the gap between cells and tumours

JS Lowengrub, HB Frieboes, F **, YL Chuang, X Li… - …, 2009‏ - iopscience.iop.org
Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …

'Go or grow': the key to the emergence of invasion in tumour progression?

H Hatzikirou, D Basanta, M Simon… - … and biology: a …, 2012‏ - academic.oup.com
Uncontrolled proliferation and abnormal cell migration are two of the main characteristics of
tumour growth. Of ultimate importance is the question what are the mechanisms that trigger …

Three-dimensional multispecies nonlinear tumor growth—I: model and numerical method

SM Wise, JS Lowengrub, HB Frieboes… - Journal of theoretical …, 2008‏ - Elsevier
This is the first paper in a two-part series in which we develop, analyze, and simulate a
diffuse interface continuum model of multispecies tumor growth and tumor-induced …

Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1

S Rathore, H Akbari, M Rozycki, KG Abdullah… - Scientific reports, 2018‏ - nature.com
The remarkable heterogeneity of glioblastoma, across patients and over time, is one of the
main challenges in precision diagnostics and treatment planning. Non-invasive in vivo …

[کتاب][B] Mathematical modeling of biological pattern formation

A Deutsch, S Dormann, A Deutsch, S Dormann - 2017‏ - Springer
The application of mathematical models to explain the dynamics of biological pattern
formation started with the work of D'Arcy Thompson who showed that mathematics cannot …

[کتاب][B] Multiscale modeling of cancer: an integrated experimental and mathematical modeling approach

V Cristini, J Lowengrub - 2010‏ - books.google.com
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining
tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial …

[کتاب][B] Reaction-transport systems: mesoscopic foundations, fronts, and spatial instabilities

V Mendez, S Fedotov, W Horsthemke - 2010‏ - books.google.com
This book is an introduction to the dynamics of reaction-diffusion systems, with a focus on
fronts and stationary spatial patterns. Emphasis is on systems that are non-standard in the …

Three-dimensional multispecies nonlinear tumor growth—II: tumor invasion and angiogenesis

HB Frieboes, F **, YL Chuang, SM Wise… - Journal of theoretical …, 2010‏ - Elsevier
We extend the diffuse interface model developed in Wise et al.(2008) to study nonlinear
tumor growth in 3-D. Extensions include the tracking of multiple viable cell species …