Oestradiol as a neuromodulator of learning and memory
Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …
as general neuromodulators of memory processes, sex steroid hormones such as the potent …
International union of basic and clinical pharmacology. XCVII. G protein–coupled estrogen receptor and its pharmacologic modulators
Estrogens are critical mediators of multiple and diverse physiologic effects throughout the
body in both sexes, including the reproductive, cardiovascular, endocrine, nervous, and …
body in both sexes, including the reproductive, cardiovascular, endocrine, nervous, and …
What have we learned about GPER function in physiology and disease from knockout mice?
Abstract Estrogens, predominantly 17β-estradiol, exert diverse effects throughout the body in
both normal and pathophysiology, during development and in reproductive, metabolic …
both normal and pathophysiology, during development and in reproductive, metabolic …
Estrogen involvement in social behavior in rodents: rapid and long-term actions
This article is part of a Special Issue (“Estradiol and cognition”). Estrogens have repeatedly
been shown to influence a wide array of social behaviors, which in rodents are …
been shown to influence a wide array of social behaviors, which in rodents are …
GPER1/GPR30 in the brain: crosstalk with classical estrogen receptors and implications for behavior
The GPER1/GPR30 is a membrane estrogen receptor (mER) that binds 17β-estradiol (17β-
E) with high affinity and is thought to play a role in cancer progression and cardiovascular …
E) with high affinity and is thought to play a role in cancer progression and cardiovascular …
Rapid effects of estradiol on aggression in birds and mice: the fast and the furious
Across invertebrates and vertebrates, steroids are potent signaling molecules that affect
nearly every cell in the organism, including cells of the nervous system. Historically …
nearly every cell in the organism, including cells of the nervous system. Historically …
Estrogenic regulation of social behavior and sexually dimorphic brain formation
It has long been known that the estrogen, 17β-estradiol (17β-E), plays a central role for
female reproductive physiology and behavior. Numerous studies have established the …
female reproductive physiology and behavior. Numerous studies have established the …
Estradiol membrane-initiated signaling in the brain mediates reproduction
Over the past few years our understanding of estrogen signaling in the brain has expanded
rapidly. Estrogens are synthesized in the periphery and in the brain, acting on multiple …
rapidly. Estrogens are synthesized in the periphery and in the brain, acting on multiple …
G protein-coupled estrogen receptor immunoreactivity in the rat hypothalamus is widely distributed in neurons, astrocytes, and oligodendrocytes, fluctuates during the …
Introduction: The membrane-associated G protein-coupled estrogen receptor 1 (GPER)
mediates the regulation by estradiol of arginine-vasopressin immunoreactivity in the …
mediates the regulation by estradiol of arginine-vasopressin immunoreactivity in the …
Is the membrane estrogen receptor, GPER1, a promiscuous receptor that modulates nuclear estrogen receptor-mediated functions in the brain?
Abstract Contribution to Special Issue on Fast effects of steroids. Estrogen signals both
slowly to regulate transcription and rapidly to activate kinases and regulate calcium levels …
slowly to regulate transcription and rapidly to activate kinases and regulate calcium levels …