Gamma interferon release assays for detection of Mycobacterium tuberculosis infection

M Pai, CM Denkinger, SV Kik… - Clinical microbiology …, 2014 - Am Soc Microbiol
Identification and treatment of latent tuberculosis infection (LTBI) can substantially reduce
the risk of develo** active disease. However, there is no diagnostic gold standard for LTBI …

[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …

RD Kanabalan, LJ Lee, TY Lee, PP Chong… - Microbiological …, 2021 - Elsevier
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology

JM Cicchese, S Evans, C Hult, LR Joslyn… - Immunological …, 2018 - Wiley Online Library
Immune responses to pathogens are complex and not well understood in many diseases,
and this is especially true for infections by persistent pathogens. One mechanism that allows …

Latent tuberculosis infection: myths, models, and molecular mechanisms

NK Dutta, PC Karakousis - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
The aim of this review is to present the current state of knowledge on human latent
tuberculosis infection (LTBI) based on clinical studies and observations, as well as …

LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis

J Wang, Q Chai, Z Lei, Y Wang, J He, P Ge… - EMBO Molecular …, 2024 - embopress.org
Chronic infections, including Mycobacterium tuberculosis (Mtb)-caused tuberculosis (TB),
can induce host immune exhaustion. However, the key checkpoint molecules involved in …

[HTML][HTML] Mycobacterium tuberculosis infections in solid organ transplantation

AK Subramanian, MI Morris… - American Journal of …, 2013 - Elsevier
The diagnosis and treatment of tuberculosis (TB) in organ transplant recipients presents
several challenges. Impediments to rapid and accurate diagnosis may lead to treatment …

Mycobacterial infections in solid organ transplant recipients

Y Meije, C Piersimoni, J Torre‐Cisneros… - Clinical Microbiology …, 2014 - Wiley Online Library
Mycobacterial infections represent a growing challenge for solid organ transplant recipients
(SOT). The adverse effects of tuberculosis (TB) therapy present a major difficulty, due to the …

A narrative review of nontuberculous mycobacterial pulmonary disease: Microbiology, epidemiology, diagnosis, and management challenges

KA Hamed, G Tillotson - Expert Review of Respiratory Medicine, 2023 - Taylor & Francis
Introduction Nontuberculous mycobacteria (NTM) are a diverse group of mycobacterial
species that are ubiquitous in the environment. They are opportunistic pathogens that can …

Unbiased identification of blood-based biomarkers for pulmonary tuberculosis by modeling and mining molecular interaction networks

A Sambarey, A Devaprasad, A Mohan, A Ahmed… - …, 2017 - thelancet.com
Efficient diagnosis of tuberculosis (TB) is met with multiple challenges, calling for a shift of
focus from pathogen-centric diagnostics towards identification of host-based multi-marker …

Recent advances in the detection of interferon-gamma as a TB biomarker

KC Januarie, OV Uhuo, E Iwuoha, U Feleni - Analytical and Bioanalytical …, 2022 - Springer
Tuberculosis (TB) is one of the main infectious diseases worldwide and accounts for many
deaths. It is caused by Mycobacterium tuberculosis usually affecting the lungs of patients …