A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

The tripeptide glutathione is found in all eukaryotic cells, and due to the
compartmentalization of biochemical processes, its synthesis takes place exclusively in the …

This review reports in detail the cellular and molecular mechanisms which regulate the bone
remodeling process in relation to oxidative stress (OS), inflammatory factors, and estrogen …

Glutathione (GSH) is a ubiquitous tripeptide that is biosynthesized in situ at high
concentrations (1–5 mM) and involved in the regulation of cellular homeostasis via multiple …

Glutathione (GSH) is a small-molecule thiol that is abundant in all eukaryotes and has key
roles in oxidative metabolism. Mitochondria, as the major site of oxidative reactions, must …

Despite varied treatment, mitigation, and prevention efforts, the global prevalence and
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …

Redox homeostasis is essential for the maintenance of diverse cellular processes. Cancer
cells have higher levels of reactive oxygen species (ROS) than normal cells as a result of …

Sexual dimorphism is a key factor to consider in the ageing process given the impact that it
has on life expectancy. The oxidative-inflammatory theory of ageing states that the ageing …

ROS are highly reactive molecules which consist of a number of diverse chemical species,
including radical and non-radical oxygen species. Oxidative stress occurs as a result of an …

Cysteine side chains can exist in distinct oxidation states depending on the pH and redox
potential of the environment, and cysteine oxidation plays important yet complex regulatory …