Single-cell RNA sequencing (scRNA-seq) identifies cell subpopulations within tissue but
does not capture their spatial distribution nor reveal local networks of intercellular …

Conventional immunohistochemistry (IHC) is a widely used diagnostic technique in tissue
pathology. However, this technique is associated with a number of limitations, including high …

Core–shell nanoparticles are at the leading edge of the hot research topics and offer a wide
range of applications in optics, biomedicine, environmental science, materials, catalysis …

INTRODUCTION Obtaining multiplexed molecular readouts from large numbers of single
cells in situ is an important technological goal to facilitate scientific discoveries in basic and …

Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …

Tissues and organs are composed of distinct cell types that must operate in concert to
perform physiological functions. Efforts to create high-dimensional biomarker catalogs of …

Semiconductor quantum dots (QDs) have become important fluorescent probes for in vitro
and in vivo bioimaging research. Their nanoparticle surfaces for versatile bioconjugation …

The understanding of biological systems at the molecular scale is increasingly reliant on the
capability of tracking miscellaneous biomolecules and their events with improved spatial …

Fluorescence and photoacoustic imaging have different advantages in cancer diagnosis;
however, combining effects in one agent normally requires a trade-off as the mechanisms …

Single-cell analysis reveals aspects of cellular physiology not evident from population-
based studies, particularly in the case of highly multiplexed methods such as mass …