Perturbations in metabolic processes are associated with diseases such as obesity, type 2
diabetes mellitus, certain infections and some cancers. A resurgence of interest in creatine …

Advancements in nanochemistry have led to the development of engineered gold
nanostructures (GNSs) with remarkable potential for a variety of dental healthcare …

The NLRP3 inflammasome is linked to sterile and pathogen-dependent inflammation, and
its dysregulation underlies many chronic diseases. Mitochondria have been implicated as …

Aerobic glycolysis, or preferential fermentation of glucose-derived pyruvate to lactate despite
available oxygen, is associated with proliferation across many organisms and conditions. To …

As one of the fundamental requirements for cell growth and proliferation, nitrogen
acquisition and utilization must be tightly regulated. Nitrogen can be generated from amino …

Pancreatic ductal adenocarcinoma is particularly metastatic, with dismal survival rates and
few treatment options. Stiff fibrotic stroma is a hallmark of pancreatic tumours, but how …

Obesity is a major risk factor for adverse outcomes in breast cancer; however, the underlying
molecular mechanisms have not been elucidated. To investigate the role of crosstalk …

The review focuses on mechanistic evidence for the link between obesity and breast cancer.
According to the IARC study, there is sufficient evidence that obesity is closely related to a …

Creatine is a nitrogen-containing organic acid naturally existing in mammals. It can be
converted into phosphocreatine to provide energy for muscle and nerve tissues. Creatine …

Glioblastoma (GBM) is a malignancy dominated by the infiltration of tumor-associated
myeloid cells (TAMCs). Examination of TAMC metabolic phenotypes in mouse models and …