Alzheimer's disease is a devastating neurodegenerative disorder with no cure. Countless
promising therapeutics have shown efficacy in rodent Alzheimer's disease models yet failed …

Induced pluripotent stem cell (iPSC)-based disease modelling and the cell replacement
therapy approach have proven to be very powerful and instrumental in biomedical research …

Cell therapies have emerged as a promising therapeutic modality with the potential to treat
and even cure a diverse array of diseases. Cell therapies offer unique clinical and …

Neurodegenerative diseases are disabling and fatal neurological disorders that currently
lack effective treatment. Neural stem cell (NSC) transplantation has been studied as a …

The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for
personalized cell therapies and ushered in new opportunities for regenerative medicine …

The promise of human induced pluripotent stem cells (iPSCs) lies in their ability to serve as
a starting material for autologous, or patient‐specific, stem cell–based therapies. Since the …

Pluripotent stem cells offer the potential for an unlimited source for cell therapy products.
However, there is concern regarding the tumorigenicity of these products in humans, mainly …

Cell culture‐conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs)
for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect …

Recapitulation of embryonic pancreatic development has enabled development of methods
for in vitro islet cell differentiation using human pluripotent stem cells (hPSCs), which have …

Personalized medicine aims to provide tailored medical treatment that considers the clinical,
genetic, and environmental characteristics of patients. iPSCs have attracted considerable …