Alignment-free sequence analyses have been applied to problems ranging from whole-
genome phylogeny to the classification of protein families, identification of horizontally …

Whole-genome sequencing of bacteria has recently emerged as a cost-effective and
convenient approach for addressing many microbiological questions. Here, we review the …

The human gut microbiota has gained interest as an environmental factor that may
contribute to health or disease. The development of next-generation probiotics is a …

Nucleotide-based intergenomic similarities are useful to understand how viruses are related
with each other and to classify them. Here we have developed VIRIDIC, which implements …

Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …

The cyclic oligonucleotide-based antiphage signalling system (CBASS) and the pyrimidine
cyclase system for antiphage resistance (Pycsar) are antiphage defence systems in diverse …

A mysterious feature of Crohn's disease (CD) is the extra-intestinal manifestation of"
cree** fat"(CrF), defined as expansion of mesenteric adipose tissue around the inflamed …

Background Plastome (plastid genome) sequences provide valuable information for
understanding the phylogenetic relationships and evolutionary history of plants. Although …

New genome assemblies have been arriving at a rapidly increasing pace, thanks to
decreases in sequencing costs and improvements in third-generation sequencing …

Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …