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[HTML][HTML] Structural insight into the mechanisms and interacting features of endocrine disruptor Bisphenol A and its analogs with human estrogen-related receptor …
RK Pathak, JM Kim - Environmental Pollution, 2024 - Elsevier
Bisphenol A (BPA) is a very important chemical from the commercial perspective. Many
useful products are made from it, so its production is increasing day by day. It is widely …
useful products are made from it, so its production is increasing day by day. It is widely …
Estrogen receptor alpha binders for hormone-dependent forms of breast cancer: e-QSAR and molecular docking supported by X-ray resolved structures
VH Masand, SA Al-Hussain, AY Alzahrani… - ACS …, 2024 - ACS Publications
Cancer, a life-disturbing and lethal disease with a high global impact, causes significant
economic, social, and health challenges. Breast cancer refers to the abnormal growth of …
economic, social, and health challenges. Breast cancer refers to the abnormal growth of …
Evaluation of the estrogenic/antiestrogenic activities of perfluoroalkyl substances and their interactions with the human estrogen receptor by combining in vitro assays …
J Li, H Cao, H Feng, Q Xue, A Zhang… - Environmental Science & …, 2020 - ACS Publications
The potential estrogenic activities of perfluoroalkyl substances (PFASs) are controversial.
Here, we investigated the estrogenic/antiestrogenic activities of PFASs and explored the …
Here, we investigated the estrogenic/antiestrogenic activities of PFASs and explored the …
[HTML][HTML] Fluorene-9-bisphenol regulates steroidogenic hormone synthesis in H295R cells through the AC/cAMP/PKA signaling pathway
Y Huang, W Zhang, N Cui, Z **ao, W Zhao… - Ecotoxicology and …, 2022 - Elsevier
Abstract Fluorene-9-bisphenol (BHPF), which has been used as a substitute for bisphenol A
(BPA) in consumer goods and industrial products, can be detected in environmental media …
(BPA) in consumer goods and industrial products, can be detected in environmental media …
Chemicals of environmental concern as inhibitors of human placental 3β-hydroxysteroid dehydrogenase 1 and aromatase: Screening and docking analysis
L Tang, L Shi, Y Tang, Y Ying, Y Dong, H Li… - Chemico-biological …, 2022 - Elsevier
Many environmental pollutants act as endocrine-disrupting compounds by inhibiting human
placental 3β-hydroxysteroid dehydrogenase/Δ 5-4 isomerase type 1 (HSD3B1) and …
placental 3β-hydroxysteroid dehydrogenase/Δ 5-4 isomerase type 1 (HSD3B1) and …
Structural and energetic basis of interaction between human estrogen-related receptor γ and environmental endocrine disruptors from multiple molecular dynamics …
L Chen, X Huang, Y Li, B Zhao, M Liang… - Journal of Hazardous …, 2023 - Elsevier
Environmental endocrine disruptors (EEDs), a class of molecules that are widespread in our
environment, may adversely affect the endocrine system. Exploring the interactions between …
environment, may adversely affect the endocrine system. Exploring the interactions between …
Chronic exposure to low levels of parabens increases mammary cancer growth and metastasis in mice
JH Tong, S Elmore, SS Huang… - …, 2023 - academic.oup.com
Methylparaben (MP) and propylparaben (PP) are commonly used as food, cosmetic, and
drug preservatives. These parabens are detected in the majority of US women and children …
drug preservatives. These parabens are detected in the majority of US women and children …
[HTML][HTML] In silico simulations and molecular descriptors to predict in vitro transactivation potencies of Baikal seal estrogen receptors by environmental contaminants
HT Nguyen, Y Yoshinouchi, M Hirano… - Ecotoxicology and …, 2023 - Elsevier
Baikal seals (Pusa sibirica) are vulnerable to high levels of organic pollutants. Here, we
evaluated the transactivation potencies of bisphenols (BPs) and hydroxylated …
evaluated the transactivation potencies of bisphenols (BPs) and hydroxylated …
Structural basis for molecular recognition of G protein-coupled estrogen receptor by selected bisphenols
X Liu, Q Xue, H Zhang, J Fu, A Zhang - Science of the Total Environment, 2021 - Elsevier
Complicated ligand-dependent signaling pathways of bisphenol A (BPA) and its analogues
involve not only intranuclear estrogen receptor but also membrane receptor G protein …
involve not only intranuclear estrogen receptor but also membrane receptor G protein …
CatNet: Sequence-based deep learning with cross-attention mechanism for identifying endocrine-disrupting chemicals
L Zhao, Q Xue, H Zhang, Y Hao, H Yi, X Liu… - Journal of Hazardous …, 2024 - Elsevier
Endocrine-disrupting chemicals (EDCs) pose significant environmental and health risks due
to their potential to interfere with nuclear receptors (NRs), key regulators of physiological …
to their potential to interfere with nuclear receptors (NRs), key regulators of physiological …