A comprehensive review of advanced focused ultrasound (FUS) microbubbles-mediated treatment of Alzheimer's disease

N Rouhi, Z Chakeri, BG Nejad, M Rahimzadegan… - Heliyon, 2024 - cell.com
Alzheimer's disease (AD) is characterized by progressive neurodegeneration, memory loss,
and cognitive impairment leading to dementia and death. The blood-brain barrier (BBB) …

Ferroptosis: underlying mechanisms and involvement in neurodegenerative diseases

Y Wang, HJ Li, QX He, R Zou, JR Cai, L Zhang - Apoptosis, 2024 - Springer
Ferroptosis, a mode of cell death that was recently identified in 2012, is driven by iron-
dependent lipid peroxidation and distinct from other mechanisms of cell death such as …

Cuproptosis and Cu: a new paradigm in cellular death and their role in non-cancerous diseases

Z Yang, R Feng, H Zhao - Apoptosis, 2024 - Springer
Cuproptosis, a newly characterized form of regulated cell death driven by copper
accumulation, has emerged as a significant mechanism underlying various non-cancerous …

Unlocking hope: Therapeutic advances and approaches in modulating the WNT pathway for neurodegenerative diseases

N Faraji, N Ebadpour, M Abavisani, A Gorji - Molecular Neurobiology, 2024 - Springer
Neurodegenerative diseases (NDs) are conditions characterized by sensory, motor, and
cognitive impairments due to alterations in the structure and function of neurons in the …

Diet and Nutraceuticals for treatment and prevention of primary and secondary stroke: emphasis on nutritional antiplatelet and antithrombotic agents

R Kakarla, LA Vinjavarapu, S Krishnamurthy - Neurochemistry International, 2024 - Elsevier
Ischemic stroke is a devastating disease that causes morbidity and mortality. Malnutrition
following ischemic stroke is common in stroke patients. During the rehabilitation, the death …

The brain–gut–bone axis in neurodegenerative diseases: insights, challenges, and future prospects

R Li, Z Miao, Y Liu, X Chen, H Wang, J Su… - Advanced …, 2024 - Wiley Online Library
Neurodegenerative diseases are global health challenges characterized by the progressive
degeneration of nerve cells, leading to cognitive and motor impairments. The brain–gut …

[HTML][HTML] circRNAs as epigenetic regulators of integrity in blood–brain barrier architecture: mechanisms and therapeutic strategies in multiple sclerosis

E D'Aversa, F Salvatori, M Vaccarezza, B Antonica… - Cells, 2024 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease leading to
progressive demyelination and neuronal loss, with extensive neurological symptoms. As …

Unravelling neuroregenerative and neuroprotective roles of Wnt/β-catenin pathway in ischemic stroke: Insights into molecular mechanisms

S Yadava, DH Reddy, VP Nakka, VL Anusha… - Neuroscience, 2025 - Elsevier
Stroke is a serious condition often resulting in mortality or long-term disability, causing
cognitive, memory, and motor impairments. A reduction in cerebral blood flow below critical …

Morin attenuated the global cerebral ischemia via antioxidant, anti-inflammatory, and antiapoptotic mechanisms in rats

N Alla, S Palatheeya, SR Challa, R Kakarla - Metabolic Brain Disease, 2024 - Springer
Global cerebral ischemia is one of the major causes of memory and cognitive impairment.
Hyperactivation of acetylcholine esterase (AChE), oxidative stress, and inflammation are …

Salidroside Mediated the Nrf2/GPX4 Pathway to Attenuates Ferroptosis in Parkinson's Disease

J Shen, S Chen, X Li, L Wu, X Mao, J Jiang… - Neurochemical …, 2024 - Springer
Parkinson's Disease (PD) is characterized by the loss of dopaminergic neurons, with
ferroptosis playing a significant role. Salidroside (SAL) has shown neuroprotective potential …