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Group 1 ILCs: Heterogeneity, plasticity, and transcriptional regulation
Group 1 innate lymphoid cells (ILCs), comprising ILC1s and natural killer cells (NK cells),
belong to a large family of developmentally related innate lymphoid cells that lack …
belong to a large family of developmentally related innate lymphoid cells that lack …
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner
The maintenance of intestinal homeostasis is a fundamental process critical for organismal
integrity. Sitting at the interface of the gut microbiome and mucosal immunity, adaptive and …
integrity. Sitting at the interface of the gut microbiome and mucosal immunity, adaptive and …
[HTML][HTML] There's no place like home: How local tissue microenvironments shape the function of innate lymphoid cells
Innate lymphoid cells (ILC) have emerged as critical immune effectors with key roles in
orchestrating the wider immune response. While ILC are relatively rare cells they are found …
orchestrating the wider immune response. While ILC are relatively rare cells they are found …
[HTML][HTML] MicroRNA-142 regulates gut associated lymphoid tissues and group 3 innate lymphoid cells
The transcriptomic signatures that shape responses of innate lymphoid cells (ILCs) have
been well characterised, however post-transcriptional mechanisms which regulate their …
been well characterised, however post-transcriptional mechanisms which regulate their …
Single-cell RNA sequencing of cells from fresh or frozen tissue reveals a signature of freezing marked by heightened stress and activation
Single-cell RNA sequencing (scRNAseq) is increasingly used to decipher immune cell
functions within tissues. Sequencing human tissue lymphocytes is often performed using …
functions within tissues. Sequencing human tissue lymphocytes is often performed using …