Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …

Lysosomes are degradation centers and signaling hubs in cells and play important roles in
cellular homeostasis, development, and aging. Changes in lysosome function are essential …

Phagocytosis is a cellular process for ingesting and eliminating particles larger than 0.5 μm
in diameter, including microorganisms, foreign substances, and apoptotic cells …

Multiple modes of cell death have been identified, each with a unique function and each
induced in a setting-dependent manner. As billions of cells die during mammalian …

Extracellular vesicles (EVs) are nanoscale membrane vesicles released by donor cells that
can be taken up by recipient cells. The study of EVs has the potential to identify unknown …

Exosomes are generated within the multivesicular endosomes (MVEs) as intraluminal
vesicles (ILVs) and secreted during the fusion of MVEs with the cell membrane. The …

Lysosomes are the main proteolytic compartments of mammalian cells comprising of a
battery of hydrolases. Lysosomes dispose and recycle extracellular or intracellular …

Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

Coxiella burnetii is the agent of Q fever, or “query fever,” a zoonosis first described in
Australia in 1937. Since this first description, knowledge about this pathogen and its …

One hundred years have passed since the death of Élie Metchnikoff (1845–1916). He was
the first to observe the uptake of particles by cells and realized the importance of this …