Mucosal-associated invariant T (MAIT) cells are unique innate-like T cells that bridge innate
and adaptive immunity. They are activated by conserved bacterial ligands derived from …

Diet is an important lifestyle factor that is known to contribute in the development of human
disease. It is well established that poor diet plays an active role in exacerbating metabolic …

Intestinal inflammation shifts microbiota composition and metabolism. How the host monitors
and responds to such changes remains unclear. Here, we describe a protective mechanism …

The intestinal microbiota plays a crucial role in influencing the development of host
immunity, and in turn the immune system also acts to regulate the microbiota through …

Abstract Mucosal Associated Invariant T (MAIT) cells are evolutionary conserved innate-like
T cells able to recognize bacterial and fungal ligands derived from vitamin B biosynthesis …

Mucosal-associated invariant T (MAIT) cells are an evolutionarily conserved T cell subset,
which reacts to most bacteria through T cell receptor (TCR)-mediated recognition of …

MR1T cells are a recently found class of T cells that recognize antigens presented by the
major histocompatibility complex-I–related molecule MR1 in the absence of microbial …

As researchers are increasingly able to collect data on a large scale from multiple clinical
and omics modalities, multi-omics integration is becoming a critical component of …

MHC antigen presentation plays a fundamental role in adaptive and semi-invariant T cell
immunity. Distinct MHC molecules bind antigens that differ in chemical structure, origin and …

MAIT cells are innate-like T cells residing in barrier tissues such as the lung, skin, and
intestine. Both the semi-invariant T cell receptor of MAIT cells and the restricting element …