High-throughput screening: today's biochemical and cell-based approaches
Highlights•Self-contained overview of current high-throughput screening technologies.•
Expands on the current use of most recent tools, like high-throughput microscopy.•Learn …
Expands on the current use of most recent tools, like high-throughput microscopy.•Learn …
Three-dimensional in vitro cell culture models for efficient drug discovery: Progress so far and future prospects
Despite tremendous advancements in technologies and resources, drug discovery still
remains a tedious and expensive process. Though most cells are cultured using 2D …
remains a tedious and expensive process. Though most cells are cultured using 2D …
Artificial intelligence in early drug discovery enabling precision medicine
Introduction: Precision medicine is the concept of treating diseases based on environmental
factors, lifestyles, and molecular profiles of patients. This approach has been found to …
factors, lifestyles, and molecular profiles of patients. This approach has been found to …
Recent advances in microfluidics for drug screening
J Sun, AR Warden, X Ding - Biomicrofluidics, 2019 - pubs.aip.org
With ever increasing drug resistance and emergence of new diseases, demand for new drug
development is at an unprecedented urgency. This fact has led to extensive recent efforts to …
development is at an unprecedented urgency. This fact has led to extensive recent efforts to …
Organotypic cancer tissue models for drug screening: 3D constructs, bioprinting and microfluidic chips
Highlights•3D cultures are more advantageous than monolayers as biomimetics for drug
screening.•Bioprinting constructs complex tissue models that serve in vitro drug …
screening.•Bioprinting constructs complex tissue models that serve in vitro drug …
Integrated membranes within centrifugal microfluidic devices: A review
KC O'Connell, JP Landers - Lab on a Chip, 2023 - pubs.rsc.org
Centrifugal microfluidics has evolved into a sophisticated technology capable of enabling
the exploration of fundamental questions in such fields as protein analysis, environmental …
the exploration of fundamental questions in such fields as protein analysis, environmental …
Internal flow in sessile droplets induced by substrate oscillation: towards enhanced mixing and mass transfer in microfluidic systems
The introduction of flows within sessile droplets is highly effective for many lab-on-a-chip
chemical and biomedical applications. However, generating such flows is difficult due to the …
chemical and biomedical applications. However, generating such flows is difficult due to the …
Microfluidic nanodevices for drug sensing and screening applications
The outbreak of pandemics (eg, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2 in 2019), influenza A viruses (H1N1 in 2009), etc.), and worldwide spike in the aging …
CoV-2 in 2019), influenza A viruses (H1N1 in 2009), etc.), and worldwide spike in the aging …
Parallelized Raman difference spectroscopy for the investigation of chemical interactions
Raman spectroscopy provides an extremely high chemical selectivity. Raman difference
spectroscopy is a technique to reveal even the smallest differences that occur due to weak …
spectroscopy is a technique to reveal even the smallest differences that occur due to weak …
Tailored fluorosurfactants through controlled/living radical polymerization for highly stable microfluidic droplet generation
Droplet‐based microfluidics represents a disruptive technology in the field of chemistry and
biology through the generation and manipulation of sub‐microlitre droplets. To avoid droplet …
biology through the generation and manipulation of sub‐microlitre droplets. To avoid droplet …