Diagnosis of invasive fungal infections: challenges and recent developments

W Fang, J Wu, M Cheng, X Zhu, M Du, C Chen… - Journal of biomedical …, 2023 - Springer
Background The global burden of invasive fungal infections (IFIs) has shown an upsurge in
recent years due to the higher load of immunocompromised patients suffering from various …

[HTML][HTML] Diagnostic test accuracy of the BioFire® FilmArray® meningitis/encephalitis panel: a systematic review and meta-analysis

GS Tansarli, KC Chapin - Clinical Microbiology and Infection, 2020 - Elsevier
Abstract Background The FilmArray® meningitis/encephalitis (ME) panel is a multiplex PCR
assay which can detect the most commonly identified pathogens in central nervous system …

Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a assay

X Ding, K Yin, Z Li, RV Lalla, E Ballesteros… - Nature …, 2020 - nature.com
The recent outbreak of novel coronavirus (SARS-CoV-2) causing COVID-19 disease
spreads rapidly in the world. Rapid and early detection of SARS-CoV-2 facilitates early …

All-in-one dual CRISPR-Cas12a (AIOD-CRISPR) assay: a case for rapid, ultrasensitive and visual detection of novel coronavirus SARS-CoV-2 and HIV virus

X Ding, K Yin, Z Li, C Liu - BioRxiv, 2020 - pmc.ncbi.nlm.nih.gov
A recent outbreak of novel coronavirus (SARS-CoV-2), the causative agent of COVID-19,
has spread rapidly all over the world. Human immunodeficiency virus (HIV) is another …

CRISPR systems for COVID-19 diagnosis

H Rahimi, M Salehiabar, M Barsbay, M Ghaffarlou… - ACS …, 2021 - ACS Publications
The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019,
which has spread rapidly and become a global pandemic. The number of cases of COVID …

Biofire FilmArray Meningitis/Encephalitis panel for the aetiological diagnosis of central nervous system infections: a systematic review and diagnostic test accuracy …

J Trujillo-Gómez, S Tsokani, C Arango-Ferreira… - …, 2022 - thelancet.com
Summary Background The FilmArray Meningitis/Encephalitis (FA/ME) panel brings benefits
in clinical practice, but its diagnostic test accuracy (DTA) remains unclear. We aimed to …

An update on current and novel molecular diagnostics for the diagnosis of invasive fungal infections

JD Jenks, PL White, SE Kidd, T Goshia… - Expert review of …, 2023 - Taylor & Francis
Background Invasive fungal infections cause millions of infections annually, but diagnosis
remains challenging. There is an increased need for low-cost, easy to use, highly sensitive …

Syndromic diagnostic testing: a new way to approach patient care in the treatment of infectious diseases

LE Dumkow, LJ Worden, SN Rao - Journal of Antimicrobial …, 2021 - academic.oup.com
Advanced microbiology technologies such as multiplex molecular assays (ie syndromic
diagnostic tests) are a novel approach to the rapid diagnosis of common infectious diseases …

Molecular diagnostics for invasive fungal diseases: Current and future approaches

D Pham, V Sivalingam, HM Tang, JM Montgomery… - Journal of Fungi, 2024 - mdpi.com
Invasive fungal diseases (IFDs) comprise a growing healthcare burden, especially given the
expanding population of immunocompromised hosts. Early diagnosis of IFDs is required to …

Rapid and sensitive detection of Ebola RNA in an unamplified sample based on CRISPR-Cas13a and DNA roller machine

XM Hang, PF Liu, S Tian, HY Wang, KR Zhao… - Biosensors and …, 2022 - Elsevier
A fast and simple Cas13a-based assay approach for direct detecting Ebola RNA in
unamplified samples is reported. The procedure (named Cas-Roller) is comprised of a 10 …