As the pulsatile cardiac blood flow drives the heart valve leaflets to open and close, the flow
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …

The heart pumps blood to maintain circulation and ensure the delivery of oxygenated blood
to all the organs of the body. Mechanics play a critical role in governing and regulating heart …

Mitral regurgitation is one of the most common forms of heart valve disorder, which may
result in heart failure. Due to the rapid ageing of the population, surgical repair and …

Mitral valve (MV) dynamics depends on a force balance across the mitral leaflets, the
chordae tendineae, the mitral annulus, the papillary muscles and the adjacent ventricular …

Despite their seemingly delicate appearance, thin biological membranes fulfill various
crucial roles in the human body and can sustain substantial mechanical loads. Unlike …

In this paper, three different constitutive laws for mitral leaflets and two laws for chordae
tendineae are selected to study their effects on mitral valve dynamics with fluid-structure …

Background Mitral valve failure can require repair or replacement. Replacement
bioprosthetic valves are treated with glutaraldehyde prior to implantation. The aim of this …

The tricuspid annulus shows significant alterations in patients with functional tricuspid
regurgitation–tricuspid valve dysfunction that is secondary to other diseases such as …

Computational models of the heart's mitral valve (MV) exhibit potential for preoperative
surgical planning in ischemic mitral regurgitation (IMR). However challenges exist in …

The geometrical details and biomechanical relationships of the mitral valve–left ventricular
apparatus are very complex and have posed as an area of research interest for decades …