How development sculpts hippocampal circuits and function

R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …

Non-invasive temporal interference electrical stimulation of the human hippocampus

IR Violante, K Alania, AM Cassarà, E Neufeld… - Nature …, 2023 - nature.com
Deep brain stimulation (DBS) via implanted electrodes is used worldwide to treat patients
with severe neurological and psychiatric disorders. However, its invasiveness precludes …

Neural oscillations: understanding a neural code of pain

JA Kim, KD Davis - The Neuroscientist, 2021 - journals.sagepub.com
Neural oscillations play an important role in the integration and segregation of brain regions
that are important for brain functions, including pain. Disturbances in oscillatory activity are …

Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices

JP Andrews, J Geng, K Voitiuk, MAT Elliott, D Shin… - Nature …, 2024 - nature.com
Seizures are made up of the coordinated activity of networks of neurons, suggesting that
control of neurons in the pathologic circuits of epilepsy could allow for control of the disease …

Primacy of vision shapes behavioral strategies and neural substrates of spatial navigation in marmoset hippocampus

DB Piza, BW Corrigan, RA Gulli, S Do Carmo… - Nature …, 2024 - nature.com
The role of the hippocampus in spatial navigation has been primarily studied in nocturnal
mammals, such as rats, that lack many adaptations for daylight vision. Here we demonstrate …

The interictal suppression hypothesis in focal epilepsy: network-level supporting evidence

GW Johnson, DJ Doss, VL Morgan, DL Paulo, LY Cai… - Brain, 2023 - academic.oup.com
Why are people with focal epilepsy not continuously having seizures? Previous neuronal
signalling work has implicated gamma-aminobutyric acid balance as integral to seizure …

Altered excitatory and inhibitory neuronal subpopulation parameters are distinctly associated with tau and amyloid in Alzheimer's disease

KG Ranasinghe, P Verma, C Cai, X **e, K Kudo, X Gao… - Elife, 2022 - elifesciences.org
Background: Neuronal-and circuit-level abnormalities of excitation and inhibition are shown
to be associated with tau and amyloid-beta (Aβ) in preclinical models of Alzheimer's disease …

Human connectome topology directs cortical traveling waves and shapes frequency gradients

DP Koller, M Schirner, P Ritter - Nature Communications, 2024 - nature.com
Traveling waves and neural oscillation frequency gradients are pervasive in the human
cortex. While the direction of traveling waves has been linked to brain function and …

Phase precession in the human hippocampus and entorhinal cortex

SE Qasim, I Fried, J Jacobs - Cell, 2021 - cell.com
Knowing where we are, where we have been, and where we are going is critical to many
behaviors, including navigation and memory. One potential neuronal mechanism underlying …

Spatial modulation of hippocampal activity in freely moving macaques

D Mao, E Avila, B Caziot, J Laurens, JD Dickman… - Neuron, 2021 - cell.com
The hippocampal formation is linked to spatial navigation, but there is little corroboration
from freely moving primates with concurrent monitoring of head and gaze stances. We …