Dry eye disease: identification and therapeutic strategies for primary care clinicians and clinical specialists

J Sheppard, B Shen Lee, LM Periman - Annals of medicine, 2023 - Taylor & Francis
Dry eye disease (DED) is a multifactorial disorder characterized by loss of tear film
homeostasis with an estimated worldwide prevalence of 5% to 50%. In DED, dysfunction of …

Ocular benzalkonium chloride exposure: problems and solutions

MH Goldstein, FQ Silva, N Blender, T Tran, S Vantipalli - Eye, 2022 - nature.com
Preservatives in multidose formulations of topical ophthalmic medications are crucial for
maintaining sterility but can be toxic to the ocular surface. Benzalkonium chloride (BAK) …

TFOS DEWS II definition and classification report

JP Craig, KK Nichols, EK Akpek, B Caffery, HS Dua… - The ocular …, 2017 - Elsevier
The goals of the TFOS DEWS II Definition and Classification Subcommittee were to create
an evidence-based definition and a contemporary classification system for dry eye disease …

TFOS DEWS II diagnostic methodology report

JS Wolffsohn, R Arita, R Chalmers, A Djalilian… - The ocular …, 2017 - Elsevier
The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II
Diagnostic Methodology Subcommittee was 1) to identify tests used to diagnose and monitor …

TFOS DEWS II management and therapy report

L Jones, LE Downie, D Korb, JM Benitez-del-Castillo… - The ocular …, 2017 - Elsevier
The members of the Management and Therapy Subcommittee undertook an evidence-
based review of current dry eye therapies and management options. Management options …

TFOS DEWS II tear film report

MDP Willcox, P Argüeso, GA Georgiev, JM Holopainen… - The ocular …, 2017 - Elsevier
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Tfos dews ii pathophysiology report

AJ Bron, CS de Paiva, SK Chauhan, S Bonini… - The ocular …, 2017 - Elsevier
Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

TFOS DEWS II report executive summary

JP Craig, JD Nelson, DT Azar, C Belmonte, AJ Bron… - The ocular …, 2017 - Elsevier
This article presents an Executive Summary of the conclusions and recommendations of the
10-chapter TFOS DEWS II report. The entire TFOS DEWS II report was published in the July …

[HTML][HTML] NOV03 for dry eye disease associated with meibomian gland dysfunction: results of the randomized phase 3 GOBI study

J Tauber, GJ Berdy, DL Wirta, S Krösser, JL Vittitow… - Ophthalmology, 2023 - Elsevier
Objective To evaluate the efficacy and safety of NOV03 (perfluorohexyloctane) ophthalmic
drop in patients with dry eye disease (DED) associated with meibomian gland dysfunction …

Artificial tears: biological role of their ingredients in the management of dry eye disease

M Labetoulle, JM Benitez-del-Castillo… - International journal of …, 2022 - mdpi.com
Dry eye disease (DED) is the most common ocular surface disease, characterized by
insufficient production and/or instability of the tear film. Tear substitutes are usually the first …