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Evolution and emergence of Mycobacterium tuberculosis
M Orgeur, C Sous, J Madacki… - FEMS microbiology …, 2024 - academic.oup.com
Tuberculosis (TB) remains one of the deadliest infectious diseases in human history,
prevailing even in the 21st century. The causative agents of TB are represented by a group …
prevailing even in the 21st century. The causative agents of TB are represented by a group …
[HTML][HTML] Consequences of genomic diversity in Mycobacterium tuberculosis
M Coscolla, S Gagneux - Seminars in immunology, 2014 - Elsevier
The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC),
comprises seven phylogenetically distinct lineages associated with different geographical …
comprises seven phylogenetically distinct lineages associated with different geographical …
Co‐evolution of Mycobacterium tuberculosis and Homo sapiens
The causative agent of human tuberculosis (TB), M ycobacterium tuberculosis, is an obligate
pathogen that evolved to exclusively persist in human populations. For M. tuberculosis to …
pathogen that evolved to exclusively persist in human populations. For M. tuberculosis to …
A new evolutionary scenario for the Mycobacterium tuberculosis complex
The distribution of 20 variable regions resulting from insertion-deletion events in the
genomes of the tubercle bacilli has been evaluated in a total of 100 strains of …
genomes of the tubercle bacilli has been evaluated in a total of 100 strains of …
Laboratory diagnosis of tuberculosis in resource-poor countries: challenges and opportunities
LM Parsons, Á Somoskövi, C Gutierrez… - Clinical microbiology …, 2011 - journals.asm.org
With an estimated 9.4 million new cases globally, tuberculosis (TB) continues to be a major
public health concern. Eighty percent of all cases worldwide occur in 22 high-burden, mainly …
public health concern. Eighty percent of all cases worldwide occur in 22 high-burden, mainly …
Ancient Origin and Gene Mosaicism of the Progenitor of Mycobacterium tuberculosis
The highly successful human pathogen Mycobacterium tuberculosis has an extremely low
level of genetic variation, which suggests that the entire population resulted from clonal …
level of genetic variation, which suggests that the entire population resulted from clonal …
Bovine tuberculosis: an old disease but a new threat to Africa
WY Ayele, SD Neill, J Zinsstag… - … of Tuberculosis and …, 2004 - ingentaconnect.com
Bovine tuberculosis (TB) is a disease characterised by progressive development of specific
granulomatous le-sions or tubercles in lung tissue, lymph nodes or other organs …
granulomatous le-sions or tubercles in lung tissue, lymph nodes or other organs …
Genomic insights into tuberculosis
JE Galagan - Nature Reviews Genetics, 2014 - nature.com
Prevalent since pre-history, human tuberculosis—caused by the pathogen Mycobacterium
tuberculosis—remains a major source of death worldwide. Moreover, increasing drug …
tuberculosis—remains a major source of death worldwide. Moreover, increasing drug …
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis
P Supply, M Marceau, S Mangenot, D Roche… - Nature …, 2013 - nature.com
Global spread and limited genetic variation are hallmarks of M. tuberculosis, the agent of
human tuberculosis. In contrast, Mycobacterium canettii and related tubercle bacilli that also …
human tuberculosis. In contrast, Mycobacterium canettii and related tubercle bacilli that also …
Impact of genotypic studies on mycobacterial taxonomy: the new mycobacteria of the 1990s
E Tortoli - Clinical microbiology reviews, 2003 - journals.asm.org
The advancement of genetic techniques has greatly boosted taxonomic studies in recent
years. Within the genus Mycobacterium, 42 new species have been detected since 1990 …
years. Within the genus Mycobacterium, 42 new species have been detected since 1990 …