Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

The brain-gut axis is a bidirectional communication system between the central nervous
system and the gastrointestinal tract. Serotonin functions as a key neurotransmitter at both …

Visceral pain is a global term used to describe pain originating from the internal organs of
the body, which affects a significant proportion of the population and is a common feature of …

Background Preclinical and clinical evidence supports the concept of bidirectional brain-gut
microbiome interactions. We aimed to determine if subgroups of irritable bowel syndrome …

Irritable bowel syndrome (IBS) is a common, symptom-based condition that has negative
effects on quality of life and costs health care systems billions of dollars each year. Until …

Despite an extensive body of reported information about peripheral and central mechanisms
involved in the pathophysiology of IBS symptoms, no comprehensive disease model has …

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder of unknown etiology.
IBS is caused by a disruption in the gut-brain axis. Given the importance of the gut …

A fundamental shift in neuroscience suggests bidirectional interaction of gut microbiota with
the healthy and dysfunctional brain. This microbiota-gut-brain axis has mainly been …

Puberty is a critical phase of life associated with physiological changes related to sexual
maturation, and represents a complex process regulated by multiple endocrine and genetic …

According to epidemiological studies, twice as many women as men are affected by irritable
bowel syndrome (IBS) in western countries, suggesting a role for sex hormones in IBS …