Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration

GTY Yau, W Tai, JC Arnold, HK Chan… - Pharmaceutical …, 2023 - Springer
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …

Current challenges and opportunities for improved cannabidiol solubility

KR Hossain, A Alghalayini, SM Valenzuela - International Journal of …, 2023 - mdpi.com
Cannabidiol (CBD), derived from the cannabis plant, has gained significant attention due to
its potential therapeutic benefits. However, one of the challenges associated with CBD …

Oral delivery of cannabidiol: revealing the formulation and absorption challenges

A Sitovs, K Logviss, L Lauberte, V Mohylyuk - Journal of Drug Delivery …, 2024 - Elsevier
Cannabidiol (CBD) is a pharmacologically active, non-psychoactive cannabinoid derived
from natural sources. Currently, it is available in prescription oral dosage forms for its anti …

Cannabidiol-loaded nanocarriers and their therapeutic applications

E Assadpour, A Rezaei, SS Das, BV Krishna Rao… - Pharmaceuticals, 2023 - mdpi.com
Cannabidiol (CBD), one of the most promising constituents isolated from Cannabis sativa,
exhibits diverse pharmacological actions. However, the applications of CBD are restricted …

The Skin and Natural Cannabinoids–Topical and Transdermal Applications

SI Filipiuc, AN Neagu, CM Uritu, BI Tamba, LE Filipiuc… - Pharmaceuticals, 2023 - mdpi.com
The chemical constituents of the Cannabis plant known as cannabinoids have been
extensively researched for their potential therapeutic benefits. The use of cannabinoids …

[HTML][HTML] Cannabidiol nanoemulsion for eye treatment–Anti-inflammatory, wound healing activity and its bioavailability using in vitro human corneal substitute

O Strnad, J Šuman, T Veverková, A Sukupová… - International Journal of …, 2023 - Elsevier
Cannabidiol (CBD) is the non-psychoactive component of the plant Cannabis sativa (L.) that
has great anti-inflammatory benefits and wound healing effects. However, its high …

Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways

BC Phukan, R Roy, I Gahatraj… - Phytotherapy …, 2023 - Wiley Online Library
Leading neurodegenerative diseases Alzheimer's disease (AD) and Parkinson's disease
(PD) are characterized by the impairment of memory and motor functions, respectively …

Cannabidiol-loaded nanostructured lipid carriers (NLCs) for dermal delivery: enhancement of photostability, cell viability, and anti-inflammatory activity

B Morakul, VB Junyaprasert, K Sakchaisri… - Pharmaceutics, 2023 - mdpi.com
The aim of this study was to encapsulate cannabidiol (CBD) extract in nanostructured lipid
carriers (NLCs) to improve the chemical stability and anti-inflammatory activity of CBD for …

Co-dispersion delivery systems with solubilizing carriers improving the solubility and permeability of cannabinoids (cannabidiol, cannabidiolic acid, and …

A Stasiłowicz-Krzemień, P Szulc, J Cielecka-Piontek - Pharmaceutics, 2023 - mdpi.com
Cannabinoids: cannabidiol (CBD), cannabidiolic acid (CBDA), and cannabichromene (CBC)
are lipophilic compounds with limited water solubility, resulting in challenges related to their …

Cannabidiol-loaded microparticles embedded in a porous hydrogel matrix for biomedical applications

C David, JF de Souza, AF Silva, G Grazioli… - Journal of Materials …, 2024 - Springer
In this study, poly (lactic-co-glycolic acid)(PLGA) microparticles loaded with cannabidiol
(CBD) were synthesized (PLGA@ CBD microparticles) and embedded up to 10 wt% in a …