The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms

R Alaggio, C Amador, I Anagnostopoulos, AD Attygalle… - Leukemia, 2022 - nature.com
We herein present an overview of the upcoming 5th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …

Improving human cancer therapy through the evaluation of pet dogs

AK LeBlanc, CN Mazcko - Nature Reviews Cancer, 2020 - nature.com
Comparative oncology clinical trials play an important and growing role in cancer research
and drug development efforts. These trials, typically conducted in companion (pet) dogs …

The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee

E Campo, ES Jaffe, JR Cook… - Blood, The Journal …, 2022 - ashpublications.org
Since the publication of the Revised European-American Classification of Lymphoid
Neoplasms in 1994, subsequent updates of the classification of lymphoid neoplasms have …

Genomic profiling for clinical decision making in lymphoid neoplasms

L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities

A Andrades, P Peinado, JC Alvarez-Perez… - Molecular cancer, 2023 - Springer
Hematological malignancies are a highly heterogeneous group of diseases with varied
molecular and phenotypical characteristics. SWI/SNF (SWItch/Sucrose Non-Fermentable) …

Advances in understanding of angioimmunoblastic T-cell lymphoma

S Chiba, M Sakata-Yanagimoto - Leukemia, 2020 - nature.com
It has been nearly half a century since angioimmunoblastic T-cell lymphoma (AITL) was
characterized in the early 1970's. Our understanding of the disease has dramatically …

Peripheral T cell lymphomas: from the bench to the clinic

D Fiore, LV Cappelli, A Broccoli, PL Zinzani… - Nature Reviews …, 2020 - nature.com
Peripheral T cell lymphomas (PTCLs) are a heterogeneous group of orphan neoplasms.
Despite the introduction of anthracycline-based chemotherapy protocols, with or without …

Therapeutic challenges in peripheral T-cell lymphoma

Y Luan, X Li, Y Luan, J Luo, Q Dong, S Ye, Y Li, Y Li… - Molecular Cancer, 2024 - Springer
Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of hematological
malignancies. Compared to our knowledge of B-cell tumors, our understanding of T-cell …

Duvelisib plus romidepsin in relapsed/refractory T cell lymphomas: a phase 1b/2a trial

SM Horwitz, AJ Nirmal, J Rahman, R Xu, E Drill… - Nature medicine, 2024 - nature.com
PI3K-δ inhibitors have shown impressive activity in lymphoid malignancies but have been
hampered by autoimmune and infectious toxicities, leading to market withdrawals. We …

Reproducing the molecular subclassification of peripheral T-cell lymphoma–NOS by immunohistochemistry

C Amador, TC Greiner, TB Heavican… - Blood, The Journal …, 2019 - ashpublications.org
Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of mature T-cell
malignancies; approximately one-third of cases are designated as PTCL–not otherwise …