Older adult participation in cancer clinical trials: a systematic review of barriers and interventions

MS Sedrak, RA Freedman, HJ Cohen… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …

[PDF][PDF] Improving representation in clinical trials and research

K Bibbins-Domingo, A Helman - 2022 - ncbi.nlm.nih.gov
The year the issues in this report, Improving Representation in Clinical Tri als and Research,
became urgent for me was 2017. I was then chair of the US Preventive Services Task Force …

Seven knowledge gaps in modern biogerontology

SIS Rattan - Biogerontology, 2024 - Springer
About a year ago, members of the editorial board of Biogerontology were requested to
respond to a query by the editor-in-chief of the journal as to what one question within their …

Measuring population ageing: an analysis of the Global Burden of Disease Study 2017

AY Chang, VF Skirbekk, S Tyrovolas… - The Lancet Public …, 2019 - thelancet.com
Background Traditional metrics for population health ageing tend not to differentiate
between extending life expectancy and adding healthy years. A population ageing metric …

There is nothing new under the sun: Ageism and intergenerational tension in the age of the COVID-19 outbreak

L Ayalon - International psychogeriatrics, 2020 - cambridge.org
At the time of this writing, 203 countries and territories have been affected by the COVID-19
outbreak (Worldometer, 2020 a). Older adults, in particular, are negatively impacted by this …

Biological age predictors

J Jylhävä, NL Pedersen, S Hägg - EBioMedicine, 2017 - thelancet.com
The search for reliable indicators of biological age, rather than chronological age, has been
ongoing for over three decades, and until recently, largely without success. Advances in the …

Functional versus chronological age: geriatric assessments to guide decision making in older patients with cancer

E Soto-Perez-de-Celis, D Li, Y Yuan, YM Lau… - The Lancet …, 2018 - thelancet.com
As the worldwide population ages, oncologists are often required to make difficult and
complex decisions regarding the treatment of older people (aged 65 years and older) with …

Early-life exposure to tobacco, genetic susceptibility, and accelerated biological aging in adulthood

F Cui, L Tang, D Li, Y Ma, J Wang, J ** severe illness from COVID-19 and of dying from it increases with age.
This statistical association has led to numerous highly problematic policy suggestions and …

Determination of biological age: geriatric assessment vs biological biomarkers

LWM Diebel, K Rockwood - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Biological age is the concept of using biophysiological
measures to more accurately determine an individual's age-related risk of adverse …