Nitric oxide (NO), generated from L-arginine and oxygen by NO synthases, is a pleiotropic
signaling molecule involved in cardiovascular and metabolic regulation. More recently, an …

In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

The source of dietary nitrate (NO3) is mainly green, leafy vegetables, partially absorbed into
blood through intestinal mucosa. The recycled nitrate is reabsorbed and concentrated by the …

Abstract Dietary nitrates (NO3-) are naturally occurring compounds in various vegetables,
especially beetroot, which is mainly supplemented in the form of BRJ. Dietary nitrates (NO3-) …

Current research has described improving multisystem disease and organ function through
dietary nitrate (DN) supplementation. They have provided some evidence that these floras …

Purpose Supplementation with inorganic nitrate to boost the nitrate-nitrite-nitric oxide (NO)
pathway, may act as a potential therapeutic agent in diabetes. The aim of this study was to …

Prevalence of obesity is increasing worldwide and type 2 diabetes to date is the most
devastating complication of obesity. Decreased nitric oxide bioavailability is a feature of …

The prevalence of obesity and diabetes is increasing worldwide. Obesity and diabetes are
associated with oxidative stress, inflammation, endothelial dysfunction, insulin resistance …

Objectives: Dietary nitrate supplementation has been shown to lower blood pressure (BP)
particularly in short-term clinical trials. Whether these effects are sustained in the long-term …

Purpose Reduced bioavailability of nitric oxide (NO) is associated with pathogenesis of type
2 diabetes. Nitrite can act as a substrate for generation of systemic NO. The aim of this study …